[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630771":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":17,"locations":27,"responsibleParty":44,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":10,"maxAge":10,"enrollmentInfo":55,"targetDuration":58,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Tianjin Medical University General Hospital","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Monogenic Diabetes",null,[12],"Other: No Interventions",[14],{"type":6,"name":15,"description":15,"armGroupLabels":16,"otherNames":10},"No Interventions",[9],[18,23],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Ming Liu","CONTACT","+86 022-27813550","mingliu@tmu.edu.cn",{"name":24,"role":20,"phone":25,"phoneExt":10,"email":26},"Hua Shu","+86 15010106182","shuhuawelcome@163.com",[28],{"facility":29,"status":30,"city":31,"state":10,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Tianjin medical university general hospital","RECRUITING","Tianjin","300052","China","CN",{"type":36,"coordinates":37},"Point",[38,39],117.17667,39.14222,{"lat":39,"lon":38},[42,43],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},{"name":24,"role":20,"phone":25,"phoneExt":10,"email":26},{"type":45,"investigatorFullName":24,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Doctor","100630771","china-monogenic-diabetes-registry-100630771",false,"NCT07492004","China Monogenic Diabetes Registry","CMDR","Inclusion Criteria:\n\n1. Diabetes diagnosed before 25 years of age; OR diabetes diagnosed before 35 years of age with ≥1 first-degree relative (parent, sibling, or offspring) diagnosed with diabetes before 40 years of age\n2. Body mass index (BMI) at diagnosis 28 kg\u002Fm²\n3. Negative glutamic acid decarboxylase antibody (GAD-Ab)\n\nExclusion Criteria:\n\n1. Secondary diabetes\n2. Active malignancy or history of malignant tumor within the past 5 years","ALL",{"count":56,"type":57},5000,"ESTIMATED","5 Years","OBSERVATIONAL","This observational study aims to establish a digital registry, screening platform for patients with monogenic diabetes using internet-based and mobile application technologies. The primary objectives are to:\n\nCharacterize the genetic landscape of monogenic diabetes in the Chinese population, including pathogenic variants and their distribution\n\nParticipants will:\n\n* Enroll in the monogenic diabetes registry via mobile application or web-based platform\n* Undergo molecular genetic testing to establish a definitive diagnosis",[62,9,63],"Neonatal Diabetes","Maturity Onset Diabetes of the Young",[9,62,63],"2026-03-19",{"date":67,"type":68},"2026-03-25","ACTUAL",{"date":70,"type":68},"2021-02-28",{"date":72,"type":57},"2030-07-31",{"name":5,"class":6},1]