[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588396":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":10,"centralContacts":33,"locations":39,"responsibleParty":51,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":78,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Infants without dyschloremia",null,"Infants with serum chloride levels within reference range before 36 weeks PMA",[13,14,15],"Other: Incomplete response","Other: Complete response","Other: Bad response",{"label":17,"type":10,"description":18,"interventionNames":19},"Infants with dyschloremia","Infants with serum chloride levels \\\u003C96 mEq\u002Fl and \\>110 mEq\u002Fl before 36 weeks PMA",[13,14,15],[21,25,29],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Incomplete response","Infants died before 36 weeks PMA, infants diagnosed to have BPD at 36 weeks PMA and infants developed major complications before 36 weeks PMA:\n\n1. \\>Stage 2 necrotizing enterocolitis according to Bell classification\n2. Hemodynamically significant patent ductus arteriosus\n3. \\>Grade 2 intraventricular hemorrhage,\n4. Retinopathy of prematurity, ICROP classification stage \\>2\n5. \\>Stage 2 cystic periventricular leukomalacia\n6. Ventricular dilatation\u002Fhydrocephalus requiring intervention",[17,9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Complete response","Infants discharged before 36 weeks PMA and infants who reached 36 weeks PMA without BPD and major complications:\n\n1. \\>Stage 2 necrotizing enterocolitis according to Bell classification\n2. Hemodynamically significant patent ductus arteriosus\n3. \\>Grade 2 intraventricular hemorrhage,\n4. Retinopathy of prematurity, ICROP classification stage \\>2\n5. \\>Stage 2 cystic periventricular leukomalacia\n6. Ventricular dilatation\u002Fhydrocephalus requiring intervention",[17,9],{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"Bad response","Infants died before 36 weeks PMA and infants diagnosed to have BPD at 36 weeks PMA",[17,9],[34],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Murat Köstü","CONTACT","+905323932616","murat.kostu@saglik.gov.tr",[40],{"facility":41,"status":10,"city":42,"state":43,"zip":10,"country":44,"countryCode":10,"cosmosGeoPoint":45,"geoPoint":50,"contacts":10},"Kanuni Sultan Suleyman Education and Research Hospital","Istanbul","Turkey","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],28.94966,41.01384,{"lat":49,"lon":48},{"type":52,"investigatorFullName":35,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Neonatologist","100588396","chloride-imbalance-in-preterm-infants-100588396",false,"NCT06940856","Chloride Imbalance in Preterm Infants","The Impact of Chloride Imbalance on BPD Development and Mortality in Preterm Infants","Inclusion Criteria:\n\n* Infants born \\\u003C32 weeks PMA or \\\u003C1500 grams\n* Infants admitted to NICU within the first 24 hours\n\nExclusion Criteria:\n\n* Infants with major congenital anomalies\n* Infants with chromosomal anomalies\n* Infants who have undergone enterostomy operation\n* Infants admitted to NICU after the first 24 hours","ALL","1 Hour","6 Weeks",{"count":65,"type":66},500,"ESTIMATED","OBSERVATIONAL","In adults and children low or high blood chloride levels are linked to the risk of death. The aim of this observational study is to determine whether there is a relationship between low or high blood chloride levels and the risk of death or long-term lung problems. We will also learn the risk factors and associated conditions of high or low blood chloride levels. We will include infants born before 32 weeks of pregnancy or have a birth weight of less than 1500 grams in the study. The main question it aims to answer is:\n\nIs there a relationship between low or high blood chloride levels in the first 4-6 weeks of life and risk of death or long-term lung problems in premature babies? We will examine the medical reports of babies who were followed up in neonatal intensive care unit over the past 5 years.",[70,71,72],"Bronchopulmonary Dysplasia (BPD)","Mortality Prediction","Chloride Disorder",[74,75,76,77],"Bronchopulmonary dysplasia","Preterm infant","Mortality","Chloride imbalance","NOT_YET_RECRUITING","2025-04-15",{"date":81,"type":82},"2025-04-23","ACTUAL",{"date":79,"type":66},{"date":85,"type":66},"2026-10-15",{"name":5,"class":6},1]