[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593052":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":147,"collaborators":18,"id":150,"slug":151,"hasResults":152,"nctId":153,"briefTitle":154,"officialTitle":154,"acronym":155,"eligibilityCriteria":156,"healthyVolunteers":152,"sex":157,"minAge":158,"maxAge":18,"enrollmentInfo":159,"targetDuration":18,"studyType":162,"phases":163,"briefSummary":165,"conditions":166,"keywords":18,"overallStatus":41,"whyStopped":18,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":179},{"fullName":5,"class":6},"Helsinki University Central Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cholecystectomy","ACTIVE_COMPARATOR","Laparoscopic cholecystectomy is done within 2 weeks after endoscopic removal of common bile duct stones.",[13],"Procedure: Laparoscopic cholecystectomy",{"label":15,"type":16,"description":17,"interventionNames":18},"Wait-and-see","NO_INTERVENTION","After endoscopic removal of common bile duct stones, patients are managed non-operatively. During the follow-up cholecystectomy will be available on demand.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Laparoscopic cholecystectomy","Laparoscopic cholecystectomy within 2 weeks after endoscopic removal of common bile duct stone",[9],[26],{"name":27,"affiliation":5,"role":28},"Panu Mentula, MD, PhD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","+358504270183","panu.mentula@hus.fi",{"name":35,"role":31,"phone":36,"phoneExt":18,"email":37},"Päivi Siironen, MD, PhD","+358504271343","paivi.siironen@hus.fi",[39,56,65,75,83,91,99,107,115,123,131,139],{"facility":40,"status":41,"city":42,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Helsinki University Hospital, Jorvi","RECRUITING","Espoo","Finland","FI",{"type":46,"coordinates":47},"Point",[48,49],24.6522,60.2052,{"lat":49,"lon":48},[52],{"name":53,"role":31,"phone":54,"phoneExt":18,"email":55},"Hanna Malmi, MD, PhD","+358505123553","hanna.malmi@hus.fi",{"facility":57,"status":58,"city":59,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":60,"geoPoint":64,"contacts":18},"Kanta-Häme Central Hospital","NOT_YET_RECRUITING","Hämeenlinna",{"type":46,"coordinates":61},[62,63],24.46434,60.99596,{"lat":63,"lon":62},{"facility":66,"status":41,"city":67,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Helsinki University Hospital, Meilahti","Helsinki",{"type":46,"coordinates":69},[70,71],24.93545,60.16952,{"lat":71,"lon":70},[74],{"name":35,"role":31,"phone":36,"phoneExt":18,"email":37},{"facility":76,"status":58,"city":77,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":78,"geoPoint":82,"contacts":18},"Pohjois-Karjala Central Hospital","Joensuu",{"type":46,"coordinates":79},[80,81],29.76316,62.60118,{"lat":81,"lon":80},{"facility":84,"status":58,"city":85,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":86,"geoPoint":90,"contacts":18},"Keski-Suomi Central Hospital","Jyväskylä",{"type":46,"coordinates":87},[88,89],25.72088,62.24147,{"lat":89,"lon":88},{"facility":92,"status":58,"city":93,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":94,"geoPoint":98,"contacts":18},"Kymenlaakso Central Hospital","Kotka",{"type":46,"coordinates":95},[96,97],26.94582,60.4664,{"lat":97,"lon":96},{"facility":100,"status":58,"city":101,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":102,"geoPoint":106,"contacts":18},"Kuopio University Hospital","Kuopio",{"type":46,"coordinates":103},[104,105],27.67703,62.89238,{"lat":105,"lon":104},{"facility":108,"status":58,"city":109,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":110,"geoPoint":114,"contacts":18},"Päijät-Häme Central Hospital","Lahti",{"type":46,"coordinates":111},[112,113],25.66151,60.98267,{"lat":113,"lon":112},{"facility":116,"status":58,"city":117,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":118,"geoPoint":122,"contacts":18},"Oulu University Hospital","Oulu",{"type":46,"coordinates":119},[120,121],25.46816,65.01236,{"lat":121,"lon":120},{"facility":124,"status":58,"city":125,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":126,"geoPoint":130,"contacts":18},"Tampere University Hospital","Tampere",{"type":46,"coordinates":127},[128,129],23.78712,61.49911,{"lat":129,"lon":128},{"facility":132,"status":58,"city":133,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":134,"geoPoint":138,"contacts":18},"Turku University Hospital","Turku",{"type":46,"coordinates":135},[136,137],22.26869,60.45148,{"lat":137,"lon":136},{"facility":140,"status":58,"city":141,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":142,"geoPoint":146,"contacts":18},"Vaasa Central Hospital","Vaasa",{"type":46,"coordinates":143},[144,145],21.61577,63.096,{"lat":145,"lon":144},{"type":28,"investigatorFullName":148,"investigatorTitle":149,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Panu Mentula","MD, PhD, Head of Emergency Surgery","100593052","cholecystectomy-after-successful-endoscopic-common-bile-duct-stone-extraction-in-elderly-100593052",false,"NCT07001423","ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly","COFFEE","Inclusion Criteria:\n\n* Common bile duct stones cleared after Endoscopic Retrograde Cholangio Pancreatography (ERCP)\n* Age \\>= 80 years or age 75-79 years with a Charlson Comorbidity index \\>=2\n* gallbladder in situ\n\nExclusion Criteria:\n\n* Acute Cholecystitis\n* Biliary Pancreatitis\n* Severe or moderately severe post-ERCP pancreatitis\n* Chronic pancreatitis\n* Bile duct pathology\n* Widespread malignancy\n* Unable to give consent","ALL","75 Years",{"count":160,"type":161},400,"ESTIMATED","INTERVENTIONAL",[164],"NA","The goal of this study is to compare safety and efficacy of laparoscopic cholecystectomy versus wait-and-see policy after endoscopic removal of common bile duct stones in elderly. The primary endpoint is a composite outcome: Death or major postoperative complications or recurrent biliary disease within 1 year after randomization.",[167,168,169],"Cholecystectomy, Laparoscopic","Choledocholithiasis","Cholelithiasis","2025-10-02",{"date":172,"type":173},"2025-10-07","ACTUAL",{"date":175,"type":161},"2025-10-03",{"date":177,"type":161},"2032-08-31",{"name":5,"class":6},12]