[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100382122":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":33,"locations":42,"responsibleParty":56,"collaborators":32,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":32,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":32,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":83,"whyStopped":32,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"The First Affiliated Hospital with Nanjing Medical University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1\u002FControl","EXPERIMENTAL","Spherical equivalent: -2.00～+2.00 D",[13],"Device: Optic coherence tomography angiography (OCTA)",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 1\u002FMyopia","Spherical equivalent: -3.00～-6.00 D",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Group 3\u002FHigh","Spherical equivalent: -6.00～-10.00 D",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Group 4\u002FSuper High","Spherical equivalent: \\\u003C-10.00",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Optic coherence tomography angiography (OCTA)","Using non-invasive, repeatable, mature device OCTA to obtain choroidal angio-map",[9,15,19,23],null,[34,39],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Zizong Hu, PhD, MD","CONTACT","+8615195960100","huzizhong@njum.edu.cn",{"name":40,"role":36,"phone":37,"phoneExt":32,"email":41},"Qinghuai Liu, PhD, MD","liuqh@njmu.edu.cn",[43],{"facility":44,"status":32,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":32},"First Affiliated Hospital of Nanjing Medical University","Nanjing","Jiangsu","210029","China","CN",{"type":51,"coordinates":52},"Point",[53,54],118.77778,32.06167,{"lat":54,"lon":53},{"type":57,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR","100382122","choroidal-change-on-octa-in-eyes-with-high-myopia-100382122",false,"NCT04255524","Choroidal Change on OCTA in Eyes With High Myopia","OCTA to Quantify the Parapapillary Choroidal Microvascular Changes in High Myopia","Inclusion Criteria:\n\n1. Spherical equivalent measurement can be included in above 4 groups\n2. Willing to be followed up in the future 10 years\n\nExclusion Criteria:\n\n1. Deny to sign the patient consent, or deny to be followed\n2. Evidence of cardiac, or diabetic, or CNS disease.\n3. Clinically diagnosed with retinal or choroidal disease\n4. Glucoma\n5. Cataract or corneal disease that influence the quality of fundus OCTA image",true,"ALL","18 Years","55 Years",{"count":70,"type":71},200,"ESTIMATED","INTERVENTIONAL",[74],"NA","Myopia is a global healthy concern, especially the high myopia and pathological myopia among Asian populations. However, its mechanism still remains largely unclear. Recent findings suggested choroidal changes might be related to the development of myopia. This study is to useOCT angiography (OCT-A) to investigate parapapillary choroidal microvasculature change in myopic eyes, and try to find the cause-and-effect relationship between choroidal change and the development of myopia.",[77,78],"Myopia, Progressive","Choroid Disease",[80,81,82],"OCTA","Myopia","Choroid","NOT_YET_RECRUITING","2020-02-02",{"date":86,"type":87},"2020-02-05","ACTUAL",{"date":89,"type":71},"2020-02-01",{"date":91,"type":71},"2030-12-31",{"name":5,"class":6},1]