[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635006":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":33,"centralContacts":38,"locations":12,"responsibleParty":47,"collaborators":49,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":12,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":12,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":75,"whyStopped":12,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":12},{"fullName":5,"class":6},"The Hong Kong Polytechnic University","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Single vision lens group","NO_INTERVENTION","Participants in single vision lens group will receive a pair of single vision lenses for 1 year after the short-term monitoring of choroidal thickness.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"D1 lens group","EXPERIMENTAL","Participants in D1 lens group will receive a pair of D1 lenses over 1 year after the short-term monitoring of choroidal thickness.",[18],"Other: Modified Defocus Incorporated Multiple Segments lens (D1)",{"label":20,"type":15,"description":21,"interventionNames":22},"D2 lens group","Participants in D2 lens group will receive a pair of D2 lenses over 1 year after the short-term monitoring of choroidal thickness.",[23],"Other: Modified Defocus Incorporated Multiple Segments lens (D2)",[25,29],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":12},"Modified Defocus Incorporated Multiple Segments lens (D1)","D1 is a modified Defocus Incorporated Multiple Segments lens that corrects the distance refraction and provides myopic defocus simultaneously",[14],{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":12},"Modified Defocus Incorporated Multiple Segments lens (D2)","D2 is a modified Defocus Incorporated Multiple Segments lens that corrects the distance refraction and provides myopic defocus simultaneously",[20],[34],{"name":35,"affiliation":36,"role":37},"Rachel Ka Man Chun, PhD","School of Optometry, The Hong Kong Polytechnic University","PRINCIPAL_INVESTIGATOR",[39,43],{"name":35,"role":40,"phone":41,"phoneExt":12,"email":42},"CONTACT","852-27664224","rachel.chun@polyu.edu.hk",{"name":44,"role":40,"phone":45,"phoneExt":12,"email":46},"Dennis Yan Yin Tse, PhD","852-27666096","dennis.tse@polyu.edu.hk",{"type":48,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[50],{"name":51,"class":52},"HOYA Lens Thailand LTD.","INDUSTRY","100635006","choroidal-response-to-the-modified-defocus-incorporated-multiple-segments-spectacle-lenses-100635006",false,"NCT07547072","Choroidal Response to the Modified Defocus Incorporated Multiple Segments Spectacle Lenses","Choroidal Responses to the Modified Defocus Incorporated Multiple Segments (DIMS) Spectacle Lenses","Inclusion Criteria:\n\n* Hong Kong Chinese\n* Age at enrolment: 6 - 13 years\n* Myopia in spherical power: -1.00D to -5.00D in both eyes\n* Astigmatism: equal or less than 2.00D\n* The sum of spherical power and astigmatism: equal or less than -7.00D\n* Anisometropia (spherical equivalent refraction (SER)): equal or less than 1.50D\n* Previous myopia progression (valid documentation dated within 2 years before screening):\n\n  * -0.50D (SER) per year or more in both eyes OR Axial length elongation: 0.27mm\u002Fyear in both eyes\n  * If myopia is initially detected during screening, eligibility requires myopia (in SER) below the 3rd percentile curve of refraction in both eyes.12\n* Best corrected visual acuity: LogMAR 0.04 or better in both eyes\n* Ocular health: no abnormalities in both internal and external ocular health\n* Binocular vision: no strabismus and other binocular abnormalities\n* Normal colour vision\n* Willing to wear the study spectacles all the time (10 hours per day, for 7 days per week)\n\nExclusion Criteria:\n\n* Previous or current treatment for myopia control (e.g., red-light therapy, atropine, orthokeratology, specialized spectacle lenses and contact lenses and oral supplements for myopic control)\n* Existing or past eye diseases or surgeries (e.g., strabismus surgery, amblyopia, oculomotor nerve palsies, corneal disease, intraocular disease, etc.) that may have an impact on vision or visual development\n* Long-term medication (intake at least 3 days\u002Fweek) or medication\u002Fsupplements that affect eye health\n* Systemic diseases that may have an impact on vision or visual development (e.g., endocrine, cardiac and respiratory diseases, diabetes, Down syndrome, etc.)\n* Allergic to cyclopentolate eye drops\n* Individuals who, in the judgment of the Investigator, are unable to cooperate and follow instructions during eye examination.",true,"ALL","6 Years","13 Years",{"count":65,"type":66},108,"ESTIMATED","INTERVENTIONAL",[69],"NA","The goal of this study is to investigate the short-term changes in choroidal thickness and efficacy of the study spectacle lenses in children. Participants will be prescribed with a pair of study spectacle lenses for daily use and visit the clinic once every week for the first month for checkup and tests. After the first month of follow-up, participants will visit at 1 month, 6- and 12-month for checkup. Choroidal thickness, axial length and refractive errors will be monitored.",[72],"Myopia",[72,74],"Choroidal thickness","NOT_YET_RECRUITING","2026-04-17",{"date":78,"type":79},"2026-04-23","ACTUAL",{"date":81,"type":66},"2026-04-25",{"date":83,"type":66},"2028-02-29",{"name":5,"class":6}]