[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622581":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":16,"locations":25,"responsibleParty":42,"collaborators":7,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":7,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":7,"enrollmentInfo":53,"targetDuration":7,"studyType":56,"phases":7,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":71,"whyStopped":7,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Heinrich-Heine University, Duesseldorf","OTHER",null,[9,13],{"name":10,"affiliation":11,"role":12},"Malte Kelm, MD","Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf","STUDY_CHAIR",{"name":14,"affiliation":11,"role":15},"Christian Jung, MD","PRINCIPAL_INVESTIGATOR",[17,21],{"name":14,"role":18,"phone":19,"phoneExt":7,"email":20},"CONTACT","+492118118567","Christian.jung@med.uni-duesseldorf.de",{"name":22,"role":18,"phone":23,"phoneExt":7,"email":24},"Lisa Dannenberg, MD","+ 49211 81 05315","LisaKristina.Dannenberg@med.uni-duesseldorf.de",[26],{"facility":27,"status":7,"city":28,"state":7,"zip":7,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"University Hospital Duesseldorf","Düsseldorf","Germany","DE",{"type":32,"coordinates":33},"Point",[34,35],6.77927,51.22319,{"lat":35,"lon":34},[38,40,41],{"name":39,"role":18,"phone":19,"phoneExt":7,"email":20},"Christian Jund, MD",{"name":22,"role":18,"phone":23,"phoneExt":7,"email":24},{"name":14,"role":15,"phone":7,"phoneExt":7,"email":7},{"type":43,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100622581","chronic-and-acute-cardiovascular-diseases-in-elderly-intensive-care-patients-100622581",false,"NCT07385482","Chronic and Acute Cardiovascular Diseases in Elderly Intensive Care Patients","Impact of Chronic and Acute Cardiovascular Diseases in Older Intensive Care Patients: A Prospective Multicenter Observational Study - VIP4","Inclusion Criteria:\n\n* 80 years or older\n* Admission to the intensive care unit\n* Signed informed consent or absence of discernible indications suggesting the presumed intention of the patient not to participate in the study.\n\nExclusion Criteria:\n\n* \\\u003C 80 years\n* Absence of informed consent\n* Discernible indications suggesting the presumed intention of the patient not to participate in the study.","ALL","80 Years",{"count":54,"type":55},4000,"ESTIMATED","OBSERVATIONAL","Very old patients are a rapidly growing and vulnerable population in acute cardiovascular care but remain underrepresented in clinical trials. Clinical outcomes in older intensive care unit (ICU) patients are determined less by chronological age than by their clinical phenotype, including cardiovascular comorbidities, frailty, polypharmacy, and functional and cognitive impairment. This prospective multicenter observational study aims to assess the impact of chronic and acute cardiovascular diseases on long-term outcomes and functional trajectories in older ICU patients. Using the international VIP research network, approximately 4,000 patients will be enrolled across different ICU specialties and healthcare systems and assessed multidimensionally using validated clinical scores. The study seeks to improve risk stratification and outcome prediction in older critically ill patients with cardiovascular disease and to address existing evidence gaps in acute cardiovascular and intensive care medicine.",[59,60,61],"Chronic Cardiovascular Disease","Acute Cardiovascular Disease","Frailty",[63,64,65,66,67,68,69,70],"older intensive care patients","intensive care unit","cardiovascular disease","frailty","multimorbidity","mortality","functional outcome","health-related quality of life","NOT_YET_RECRUITING","2026-02-03",{"date":74,"type":75},"2026-02-05","ACTUAL",{"date":77,"type":55},"2026-03-01",{"date":79,"type":55},"2027-03-01",{"name":5,"class":6},1]