[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574644":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":24,"responsibleParty":34,"collaborators":37,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":24,"eligibilityCriteria":45,"healthyVolunteers":42,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":24,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":24,"overallStatus":58,"whyStopped":24,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":24},{"fullName":5,"class":6},"Federal University of Health Science of Porto Alegre","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"whole-body electrical stimulation","EXPERIMENTAL","Performed with calibrated Miha Bodytec equipment, with electrodes on the quadriceps, hamstrings, glutes, biceps, triceps, pectorals, abdomen, trapezius, latissimus dorsi, and quadratus lumborum. A symmetrical biphasic current, 400µs pulse width, 75Hz frequency will be used. Sixteen sessions will occur twice weekly for eight weeks. In weeks 1-2, contractions last five seconds with 10 seconds rest, for 16 minutes (64 contractions). In weeks 3-5, contractions remain five seconds with five seconds rest, also lasting 16 minutes (96 contractions). In weeks 6-8, contractions\u002Frest stay at five seconds each, lasting 20 minutes (120 contractions). Initial isometric positions familiarize the patient with stimulation, followed by squats, biceps\u002Ftriceps exercises with a proprioception stick, abdominal exercises, step-up exercises, and aerobic activities (bike\u002Ftreadmill) to conclude each session.",[13],"Other: Whole-body electrical stimulation",{"label":15,"type":6,"description":16,"interventionNames":17},"Rehabilitation","There will be 16 sessions, twice a week, on alternate days, for eight weeks. It will consist of muscle strengthening exercises, using weights, ankle weights and weight training equipment. Squats, biceps and triceps exercises (with weights), knee flexion and extension (equipment with weights) and stretching will be performed. At the end of each session, patients will do aerobic exercise (bicycle or treadmill).",[18],"Other: Rehabilitation",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Whole-body electrical stimulation","Performed using Miha Bodytec equipment, properly calibrated, with electrodes on the quadriceps, hamstrings, glutes, biceps, triceps, pectorals, abdomen, trapezius, latissimus dorsi and quadratus lumborum muscles.",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Pulmonary rehabilitation program.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Jociane Schardong","CONTACT","+55 55981348114","joci_fisioufsm@yahoo.com.br",{"type":35,"investigatorFullName":30,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Principal Investigator",[38],{"name":39,"class":6},"Santa Casa de Porto Alegre","100574644","chronic-effect-of-whole-body-electrical-stimulation-in-copd-patients-100574644",false,"NCT06761963","Chronic Effect of Whole-body Electrical Stimulation in COPD Patients","Inclusion Criteria:\n\n* Diagnosis of COPD GOLD 3 and 4;\n* Age between 18 and 80 years;\n* Ability to ambulate.\n\nExclusion Criteria:\n\n* Cognitive dysfunction that prevents assessments from being carried out, as well as inability to understand and sign the informed consent form (ICF);\n* Intolerance to the electrostimulator and\u002For change in skin sensitivity;\n* Patients with stroke sequelae;\n* Recent acute myocardial infarction (two months);\n* Uncontrolled hypertension;\n* New York Heart Association grade IV heart failure or decompensated;\n* Unstable angina or arrhythmia;\n* Peripheral vascular changes in lower limbs such as deep vein thrombosis;\n* Disabling osteoarticular or musculoskeletal disease;\n* Uncontrolled diabetes (glycemia \\> 300mg\u002FdL);\n* Patients with cancer and\u002For undergoing cancer treatment;\n* Patients with systemic lupus erythematosus or other autoimmune disease;\n* Artificial cardiac pacemaker;\n* Epilepsy;\n* Hemophilia;\n* Liver and kidney diseases.","ALL","18 Years","80 Years",{"count":50,"type":51},16,"ESTIMATED","INTERVENTIONAL",[54],"NA","Randomized clinical trial. Patients with chronic obstructive pulmonary disease (COPD) GOLD III or IV will undergo 16 sessions of Whole-body Electrical Stimulation (WB-EMS) or pulmonary rehabilitation (PR), twice a week. WB-EMS will be performed in association with squats, biceps and triceps exercises, climbing up and down a step, and abdominal exercises. There will be a progression in the number of muscle contractions after the fourth (from 64 to 96) and tenth sessions (96 to 120). PR will consist of upper and lower limb strengthening exercises. Both groups will perform aerobic exercise (essential component of the pulmonary rehabilitation program). Peripheral muscle strength (dynamometry), respiratory muscle strength (maximum inspiratory and expiratory pressure), muscle thickness (ultrasound), functional capacity (6MWT), quality of life (Saint George's Respiratory Questionnaire), inflammatory profile (PCR, IL-6 e IL-10, TNFα), oxidative stress (protein oxidation, superoxide dismutase and catalase, total hydrogen sulfides, dichlorofluorescein diacetate) will be assessed before and after the 16 sessions.",[57],"Chronic Obstructive Pulmonary Disease (COPD)","NOT_YET_RECRUITING","2025-01-06",{"date":61,"type":62},"2025-01-07","ACTUAL",{"date":64,"type":51},"2025-01-20",{"date":66,"type":51},"2025-04-10",{"name":5,"class":6}]