[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625779":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":31,"collaborators":10,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":10,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":44,"enrollmentInfo":45,"targetDuration":48,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":55,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Recep Tayyip Erdogan University Training and Research Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients diagnosed with chronic kidney disease",null,"Chronic kidney disease is diagnosed if the eGFR is below 60 ml\u002Fmin\u002F1.73 m2 for at least 3 months or if the urine albumin-creatinine ratio is above 30 mg\u002Fg (proteinuria).",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Oguz KOSE, Professor Dr.","CONTACT","+90 541 348 64 65","oguz.kose@erdogan.edu.tr",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"countryCode":10,"cosmosGeoPoint":25,"geoPoint":30,"contacts":10},"Department of Periodontology of the Faculty of Dentistry of Recep Tayyip Erdogan University","Rize","Rize Province","53200","Turkey (Türkiye)",{"type":26,"coordinates":27},"Point",[28,29],40.52194,41.02083,{"lat":29,"lon":28},{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dilek KARADOĞAN","Assoc. Prof. Dr.","100625779","chronic-kidney-disease-associated-diet-100625779",false,"NCT07427069","Chronic Kidney Disease Associated Diet","The Role of Pro-Inflammatory Diet in Periodontal Tissue Destruction in Chronic Kidney Disease","Inclusion Criteria:\n\n* Being between 18 and 65 years of age\n* Being diagnosed with Chronic Kidney Disease (having an eGFR below 60 ml\u002Fmin\u002F1.73 m² for at least 3 months or a urine albumin-to-creatinine ratio above 30 mg\u002Fg (proteinuria))\n* Having at least 20 teeth\n* Not having received periodontal therapy in the last 6 months\n* Not having taken antibiotics, steroids, and\u002For nonsteroidal anti-inflammatory drugs in the last 3 weeks\n* Not having any autoimmune disease, osteoporosis, or cancer\n* Not taking immunosuppressive medications, oral contraceptives, Not taking bisphosphonates\n* Not being pregnant\n* Not having an active infectious disease (acute hepatitis, tuberculosis, AIDS)\n* Not taking chronic medications that affect periodontal tissues (cyclosporine A, phenytoin)\n* Not taking antioxidant supplements in the last 6 months\n\nExclusion Criteria:\n\n* Patients with an active infectious disease,\n* Those taking medications that could affect periodontal tissues,\n* History of endocarditis,\n* Recent antibiotic use (within 4 months),\n* Alcohol\u002Fdrug use,\n* Psychological disorders,\n* Eating disorders,\n* Dementia,\n* Pregnancy and breastfeeding,\n* Patients who did not sign the informed consent form","ALL","18 Years","65 Years",{"count":46,"type":47},100,"ESTIMATED","1 Day","OBSERVATIONAL","The goal of this observational study is to investigate the relationship between chronic kidney disease (CKD) and periodontitis, and to evaluate the potential mediating role of dietary inflammatory potential, measured by the Dietary Inflammatory Index (DII), in this association.\n\nThe main question it aims to answer is:\n\nDoes a pro-inflammatory diet, as reflected by a higher DII score, exacerbate periodontal inflammation in individuals with chronic kidney disease?\n\nParticipants will include adults diagnosed with CKD at various stages. Periodontal status will be assessed through clinical parameters such as probing depth, clinical attachment loss, and bleeding on probing. Dietary intake will be evaluated using a validated food frequency questionnaire, and DII scores will be calculated accordingly. The study will aim to observe and analyze whether dietary inflammation contributes to increased periodontal disease severity in CKD patients, potentially offering insight into modifiable risk factors relevant to both systemic and oral health.",[52,53,54],"Chronic Kidney Disease","Periodontitis","Diet, Food and Nutrition",[56,57,58,59],"Chronic kidney disease","periodontitis","diet","inflammation","NOT_YET_RECRUITING","2026-02-21",{"date":63,"type":64},"2026-02-24","ACTUAL",{"date":66,"type":47},"2026-04-20",{"date":68,"type":47},"2026-11-16",{"name":5,"class":6},1]