[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625562":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":30,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":36,"acronym":37,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":45,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":52,"overallStatus":61,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Combat-Related TBI Cohort",null,"Adults aged 18-60 years with mild to moderate combat-related traumatic brain injury enrolled within 14 days of injury. Participants will undergo standardized clinical, psychological, and pain assessments and will be followed prospectively for 6 months to evaluate the development of chronic pain.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Dmytro Dmytriiev, PhD.Professor","CONTACT","+380674309449","d.dmytriiev@superhumans.com",[19],{"facility":20,"status":10,"city":21,"state":10,"zip":10,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":10},"Superhumans War Trauma Center","Lviv","Ukraine","UA",{"type":25,"coordinates":26},"Point",[27,28],24.02324,49.83826,{"lat":28,"lon":27},{"type":31,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100625562","chronic-pain-after-combat-related-traumatic-brain-injury-ctbi-pain-study-a-prospective-cohort-study-of-pain-chronification-after-combat-related-traumatic-brain-injury-100625562",false,"NCT07424248","Chronic Pain After Combat-Related Traumatic Brain Injury (cTBI-Pain Study) A Prospective Cohort Study of Pain Chronification After Combat-Related Traumatic Brain Injury","TBI-Pain","Inclusion Criteria:\n\n* Age 18 to 60 years\n* Combat-related traumatic brain injury (blast, impact, or combined mechanism)\n* Mild to moderate traumatic brain injury\n* Enrollment within 14 days after injury\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Severe traumatic brain injury with prolonged impaired consciousness\n* Pre-existing severe psychiatric disorder unrelated to trauma\n* Chronic pain condition predating the traumatic brain injury\n* Inability to complete follow-up assessments\n* Severe medical condition limiting participation","ALL","18 Years","60 Years",{"count":43,"type":44},100,"ESTIMATED","6 Months","OBSERVATIONAL","Combat-related traumatic brain injury (cTBI), particularly blast-related injury, is frequently associated with the development of persistent and disabling chronic pain. This prospective observational cohort study aims to determine the incidence, phenotypes, and early predictors of chronic pain following mild to moderate combat-related TBI. Adults will be enrolled within 14 days of injury and followed for 6 months. The primary endpoint is clinically significant chronic pain at 3 months, defined by pain intensity and functional interference. The study will evaluate clinical, psychological, and physiological factors to develop and internally validate a prognostic model for chronic pain risk after cTBI.",[49,50,51],"Pain","Chronic Pain","Chronic Pain Due to Injury",[53,54,55,56,57,58,59,60],"Combat-related traumatic brain injury","cTBI","Blast injury","Chronic pain","Neuropathic pain","Sleep disturbance","Pain prediction","Military trauma","NOT_YET_RECRUITING","2026-02-22",{"date":64,"type":65},"2026-02-24","ACTUAL",{"date":67,"type":44},"2026-02-15",{"date":69,"type":44},"2026-12-15",{"name":5,"class":6},1]