[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584606":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":27,"locations":33,"responsibleParty":50,"collaborators":54,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":11,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":11,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":35,"whyStopped":11,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal weight participants","ACTIVE_COMPARATOR",null,[13,14],"Other: Continuous Feeding","Other: Intermittent feeding",{"label":16,"type":10,"description":11,"interventionNames":17},"Participants with obesity",[13,14],[19,23],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"Continuous Feeding","Participants will receive 24-hour continuous feeds through an NG tube",[9,16],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":11},"Intermittent feeding","Participants will receive 3 boluses of feeding per day at regular meal times through an NG tube to mimic normal meals.",[9,16],[28],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"Kelli A Lytle, PhD","CONTACT","507-255-1488","lytle.kelli@mayo.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Rochester","Minnesota","55901","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-92.4699,44.02163,{"lat":45,"lon":44},[48],{"name":29,"role":30,"phone":49,"phoneExt":11,"email":32},"503-255-1488",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Kelli A. Lytle","Principal Investigator",[55],{"name":56,"class":57},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100584606","circadian-rhythms-in-human-adipose-100584606",false,"NCT06891534","Circadian Rhythms in Human Adipose","Circadian Regulation of Human Adipose Tissue Metabolism","Inclusion Criteria:\n\n* BMI 20-25 kg\u002Fm2 or 30-37 kg\u002Fm2\n* For participants with obesity a waist-to-hip ratio of ≥0.95 in males and ≥0.90 in females.\n* sedentary\n* females: non pregnant or breastfeeding\n* ability to provide written informed consent and follow study instructions\n\nExclusion Criteria:\n\n* History of mediations that impact adipocyte\u002Flipid metabolism\n* smoking\n* insomnia\n* sleep apnea\n* sleep medication use\n* employment in night or shift work\n* extreme chronotypes\n* Allergy to lidocaine",true,"ALL","18 Years","55 Years",{"count":70,"type":71},40,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.",[77,78],"Obesity, Abdominal","Feeding Patterns",[80,81,82,83],"circadian rhythms","adipose tissue","obesity","feeding pattern","2026-04-13",{"date":86,"type":87},"2026-04-14","ACTUAL",{"date":89,"type":87},"2021-07-01",{"date":91,"type":71},"2030-12",{"name":5,"class":6},1]