[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100446815":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":46,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"The Affiliated Hospital of Xuzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"AIS group",null,"This group includes patients with acute ischemic stroke (AIS).",[13],"Genetic: Quantitative Real-time polymerase chain reaction",{"label":15,"type":10,"description":16,"interventionNames":17},"HC group","This group includes healthy controls (HC).",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"GENETIC","Quantitative Real-time polymerase chain reaction","Quantitative Real-time polymerase chain reaction of circular RNA (circRNA).",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Xingzhi Wang, MD","CONTACT","0086-13852000759","wxz1220@126.com",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Department of Neurology","RECRUITING","Xuzhou","Jiangsu","China","CN",{"type":39,"coordinates":40},"Point",[41,42],117.28386,34.20442,{"lat":42,"lon":41},[45],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100446815","circulating-circrna-in-acute-ischemic-stroke-100446815",false,"NCT05098340","Circulating circRNA in Acute Ischemic Stroke","Clinical Significance of Circulating circRNA in Acute Ischemic Stroke (CRAST)","CRAST","Inclusion Criteria:\n\n* Aged 18 years or older\n* Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan\n* Within 72 hours of symptom onset\n* Good performance status\n* Signed an approved informed consents\n\nExclusion Criteria:\n\n* a history of hemorrhagic infarction, chronic kidney\u002Fliver diseases, peripheral arterial occlusive disease, active malignant disease, and inflammatory or infectious diseases","ALL","18 Years",{"count":59,"type":60},500,"ESTIMATED","90 Days","OBSERVATIONAL","CRAST is to analyze the expression pattern of circular RNA (circRNA) by bioinformatics analysis in patients with acute ischemic stroke and healthy control. The candidate circRNA will be verified as biomarkers for the detection and prognosis of acute ischemic stroke.",[65],"Acute Ischemic Stroke",[67],"circRNA","2024-08-04",{"date":70,"type":71},"2024-08-06","ACTUAL",{"date":73,"type":71},"2020-10-01",{"date":75,"type":60},"2024-10-30",{"name":5,"class":6},1]