[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100481331":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":35,"responsibleParty":53,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":10,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"University Hospital of Ferrara","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"definite or high suspicion endocarditis",null,"All consecutive patients referred for an echocardiography (transthoracic or transesophageal approach) with a high suspicion of endocarditis and those with a confirmed diagnosis of endocarditis independently by the request will be eligible for the study.",[13],"Diagnostic Test: advanced cardiac imaging",{"label":15,"type":10,"description":16,"interventionNames":17},"negative examination with low suspicion of endocarditis","For patients with no evidence of endocarditis on their echocardiogram, data on the following will be collected: i) risk factors for endocarditis; i) size, type and position of valve prosthesis or other devices if present; iii) Duke criteria verification.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","advanced cardiac imaging","In all patients with high suspected or confirmed endocarditis at the echocardiography the following information will be collected: 1) endocarditis risk factors, 2) type, size and position of infected valve or prosthesis, 3) echocardiographic data; 4) imaging technique used for diagnosis in addition to echocardiography; 5) management of the case performed by the endocarditis team (including cardiologist, microbiologist, cardiac surgeon, radiologist); 6) Duke criteria verification; 7) management of the case (conservative or invasive); 8) antibiotic therapy prescribed and timing; 9) follow-up at one year (death, cardiac surgery, stroke, re-infection).",[9,15],[25],{"name":26,"affiliation":5,"role":27},"Rita Pavasini, MD","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Veronica Lodolini, BsC","CONTACT","0532236450","+39","ldlvnc@unife.it",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Cona","Ferrara","44124","Italy","IT",{"type":44,"coordinates":45},"Point",[46,47],11.7069,44.80583,{"lat":47,"lon":46},[50],{"name":26,"role":31,"phone":51,"phoneExt":33,"email":52},"0532237227","pvsrti@unife.it",{"type":27,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Gianluca Campo","Full Professor of Cardiology, University of Ferrara","100481331","clinical-and-diagnostic-features-of-endocarditis-100481331",false,"NCT05547607","Clinical and Diagnostic Features of Endocarditis","Observational Prospective Multicenter Study to Characterize the cLinical ANd DiagnoStiC feAtures of Endocarditis in the contemPorary Era","ENDO-LANDSCAPE","Inclusion Criteria:\n\n* Patients above the age of 18 years.\n* all consecutive patients referred for echocardiography (transthoracic or transesophageal approach) to exclude endocarditis.\n* patients with a diagnosis of endocarditis on echocardiography independently by the request for the exam.\n\nExclusion Criteria:\n\n* patient's refusal.","ALL","18 Years",{"count":67,"type":68},500,"ESTIMATED","OBSERVATIONAL","The burden of endocarditis has changed in the last years due to an increase in percutaneous valve procedures offered to a more fragile, and old population. Therefore an update in epidemiology data is necessary. The Observational prospective multicenter study to characterize the cLinical ANd DiagnoStiC feAtures of endocarditis in the contemPorary Era, (ENDO-LANDSCAPE study) is an observational, multicenter and international study. The study has two arms: retrospective and prospective.\n\nThe retrospective arm will involve collecting data from patients discharged with a diagnosis of endocarditis between 2016 and 2022. The data obtained in the retrospective arm of the study will be utilized in a power calculation to determine the sample size for the prospective arm of the study. In the prospective phase in every participating center, all patients referred for echocardiography to assess for endocarditis and those with established endocarditis independent of the screened request will be eligible. Patients will then be stratified according to the presence or abscence of endocarditis. Those with an established diagnosis of endocarditis will be prospectively followed for outcomes.",[72],"Endocarditis","2026-04-27",{"date":75,"type":76},"2026-05-01","ACTUAL",{"date":78,"type":76},"2022-09-09",{"date":80,"type":68},"2028-06-30",{"name":5,"class":6},1]