[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575642":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":25,"locations":31,"responsibleParty":56,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":76,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Sohag University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"One group of patients againg one month to 16 years old with myasthenia gravis",null,"Patients diagnosed with myasthenia gravis at the pediatric out patient clinic by clinical charactristics ,nerve study and laboratory data will be elligable for the study.\n\nInclusion Criteria:\n\n* All patients from 1 month to 16 years confirmed diagnosis of myasthenia gravis by neurological and laboratory data.\n* Care giver accept to participate in the study.",[13,14],"Diagnostic Test: All patients in this study were subjected to the followings: (A) Clinical history focusing on: Sociodemographic data: age, gender , residence,and degree of consanguinity. Full neurodevelopmental his","Diagnostic Test: EMG ,rNST,Ach R antibodies & thyroid function",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DIAGNOSTIC_TEST","All patients in this study were subjected to the followings: (A) Clinical history focusing on: Sociodemographic data: age, gender , residence,and degree of consanguinity. Full neurodevelopmental his","Thorough clinical examination:\n\n1\\. General examination including general look, vital signs and anthropometric measurements.\n\n2\\. Scale system include gross motor function and muscle power(Quantitative Myasthenia Gravis Scale) \\[36\\] 3. detailed neurological examination including motor ,sensory and reflexes. (C) Investigations:\n\n1. Electrophysiological testing:\n\n   EMG : is especially useful in diagnosis of seronegative MG and congenital myasthenic syndromes.\n\n   NCS: including repetitive nerve stimulation test (r NST)\n2. laboratory studies:\n\n   * Serology. Detection of antibodies to the AChR supports the diagnosis of JMG. In young children where AChR antibodies are negative this can lead to difficulty in differentiating from CMS.\n   * Thyroid function tests :\n3. Imaging:\n\n   • CT chest: Although thymoma in children is rare, the thymus must be imaged once JMG has been diagnosed.\n4. molecular studies (when possible).",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"EMG ,rNST,Ach R antibodies & thyroid function","C) Investigations:\n\n1. Electrophysiological testing:\n\n   EMG : is especially useful in diagnosis of seronegative MG and congenital myasthenic syndromes.\n\n   NCS: including repetitive nerve stimulation test (r NST)\n2. laboratory studies:\n\n   * Serology. Detection of antibodies to the AChR supports the diagnosis of JMG. In young children where AChR antibodies are negative this can lead to difficulty in differentiating from CMS.\n   * Thyroid function tests :\n3. Imaging:\n\n   • CT chest: Although thymoma in children is rare, the thymus must be imaged once JMG has been diagnosed.\n4. molecular studies (when possible).",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Menna Mohamed","CONTACT","01011707915","Mena011195@med.sohag.edu.eg",[32,44,49],{"facility":33,"status":10,"city":34,"state":35,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":10},"Sohag University Hospital","Sohag","Sohag Governorate","Egypt","EG",{"type":39,"coordinates":40},"Point",[41,42],31.69478,26.55695,{"lat":42,"lon":41},{"facility":45,"status":10,"city":34,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":46,"geoPoint":48,"contacts":10},"Sohag university",{"type":39,"coordinates":47},[41,42],{"lat":42,"lon":41},{"facility":45,"status":10,"city":34,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":50,"geoPoint":52,"contacts":53},{"type":39,"coordinates":51},[41,42],{"lat":42,"lon":41},[54],{"name":55,"role":28,"phone":29,"phoneExt":29,"email":30},"Menna Mohamed Resident doctor of pediatric at El Helal hospital, Resident doctor of pediatric",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Menna Mohamed Sedik","Resident doctor of pediatric in ElHelal Hospital in Sohag","100575642","clinical-and-laboratory-profile-of-myasthenia-gravis-in-children-at-sohag-university-hospitals-100575642",false,"NCT06774937","Clinical and Laboratory Profile of Myasthenia Gravis in Children At Sohag University Hospitals","Inclusion Criteria:\n\n* All patients from 1 month to 16 years confirmed diagnosis of myasthenia gravis by neurological and laboratory data.\n\nCare giver accept to participate in the study.\n\nExclusion Criteria:\n\n* Failure to obtain informed consent. Other neurological and neuromuscular disorders. Age above 16 years.","ALL","1 Month","16 Years",{"count":70,"type":71},20,"ESTIMATED","OBSERVATIONAL","This study includes clinical and laboratory studies of patients with Myathenia gravis at Sohag Neurology outpatient clinic of pediatric department",[75],"Myasthenia Gravis in Children","NOT_YET_RECRUITING","2025-01-13",{"date":79,"type":80},"2025-01-14","ACTUAL",{"date":82,"type":71},"2025-02-01",{"date":84,"type":71},"2025-08-01",{"name":5,"class":6},3]