[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511727":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":33,"locations":43,"responsibleParty":59,"collaborators":32,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":32,"eligibilityCriteria":66,"healthyVolunteers":63,"sex":67,"minAge":68,"maxAge":68,"enrollmentInfo":69,"targetDuration":32,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":46,"whyStopped":32,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Samara State Medical University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"20 patients with zirconia","EXPERIMENTAL","patients who will receive crowns from zirconia",[13],"Diagnostic Test: dental prosthetics, biofilm response and oral microbiota",{"label":15,"type":10,"description":16,"interventionNames":17},"20 e-max patients","patients who will receive crowns from e-max",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"20 patients Cobalt-chromium alloy","patients who will receive crowns from Cobalt-chromium alloy",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"20 patients metal-ceramics","patients who will receive crowns from metal-ceramics",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DIAGNOSTIC_TEST","dental prosthetics, biofilm response and oral microbiota","microbiota, biofilm, oral mucosa",[15,19,23,9],null,[34,39],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Alexander Nesterov","CONTACT","+79276962515","Nesterov003@rambler.ru",{"name":40,"role":36,"phone":41,"phoneExt":32,"email":42},"Vladislav Karyashov","+79879593988","stomkvv@gmail.com",[44],{"facility":45,"status":46,"city":47,"state":32,"zip":32,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Gbuz So Sspn3","RECRUITING","Samara","Russia","RU",{"type":51,"coordinates":52},"Point",[53,54],50.13553,53.20767,{"lat":54,"lon":53},[57],{"name":58,"role":36,"phone":41,"phoneExt":32,"email":42},"Vladislav Kartashov",{"type":60,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR","100511727","clinical-and-microbiological-approach-in-orthopedic-treatment-of-patients-when-choosing-a-structural-material-100511727",false,"NCT05943197","Clinical and Microbiological Approach in Orthopedic Treatment of Patients When Choosing a Structural Material","Inclusion Criteria:\n\n\\- need for prosthetics\n\nExclusion Criteria:\n\n\\- lack of indications for treatment","ALL","1 Month",{"count":70,"type":71},80,"ESTIMATED","INTERVENTIONAL",[74],"NA","Today, there is a wide range of structural materials on the market, different in chemical, physical and biological properties, and information about them is very often limited only by the manufacturer's instructions, which allows to determine, at best, only the scope. In this regard, there are difficulties in choosing the optimal material for this particular situation, since without a thorough approach to studying the properties of the main materials used in dentistry, it seems difficult to provide high-quality dental care, the result of which is functional usefulness, aesthetics and durability.The problem of an individual approach to the choice of structural material from the standpoint of personalized medicine is even less studied - there are no data in the literature on the role of normal and pathogenic microflora in the development of destructive changes in structures and the development of complications, taking into account a personalized approach when analyzing the composition of the microbiota of the oral cavity, biochemical parameters of the oral fluid, blood depending on the material from which the structure is made.",[77],"Oral Microbiota",[79],"microbiota","2024-12-31",{"date":82,"type":83},"2025-01-01","ACTUAL",{"date":85,"type":83},"2023-06-01",{"date":87,"type":71},"2025-04-01",{"name":5,"class":6},1]