[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632663":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":10,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":25,"enrollmentInfo":26,"targetDuration":10,"studyType":29,"phases":10,"briefSummary":30,"conditions":31,"keywords":36,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients with Lumbar Disc Disease",null,"Adult patients aged 18-70 years presenting with clinical symptoms suggestive of lumbar disc disease (low back pain with or without radiculopathy) and MRI-confirmed lumbar disc pathology. These participants will undergo standard clinical evaluations, including pain (VAS) and disability (ODI) assessments, alongside a standardized lumbar spine MRI to correlate clinical parameters with imaging findings.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mina Mokhlis Momtaz","Resident at Orthopedic Surgery Department, Assiut University","100632663","clinical-and-mri-findings-in-lumbar-disc-disease-100632663",false,"NCT07516613","Clinical and MRI Findings in Lumbar Disc Disease","Correlation Between Clinical Parameters and MRI Imaging Findings in Lumbar Disc Disease","Inclusion Criteria:\n\n* Adult patients aged 18-70 years presenting with clinical symptoms suggestive of lumbar disc disease (low back pain with or without radiculopathy).\n* Patients with MRI-confirmed lumbar disc pathology (disc bulge, protrusion, extrusion, or sequestration) at one or more levels.\n* Patients who have had lumbar MRI performed within 3 months prior to enrollment.\n* Patients able to communicate clearly and complete assessment questionnaires.\n* Patients providing written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Patients with previous lumbar spine surgery.\n* Patients with spinal fractures, tumors, infections, or inflammatory spondyloarthropathies (e.g., ankylosing spondylitis).\n* Patients with severe psychiatric disorders that interfere with assessment.\n* Patients with contraindications to MRI (e.g., pacemakers, metallic implants).\n* Patients with cauda equina syndrome requiring emergency surgical intervention.\n* Patients with peripheral neuropathy from systemic causes (e.g., diabetes mellitus with confirmed neuropathy, renal failure).\n* Pregnant women.\n* Patients who refuse to participate or provide informed consent.","ALL","18 Years","70 Years",{"count":27,"type":28},96,"ESTIMATED","OBSERVATIONAL","Low back pain related to lumbar disc disease is a very common condition. Doctors frequently use Magnetic Resonance Imaging (MRI) to look at the spine and diagnose these problems. However, it is not always clear how well the severity of the damage seen on an MRI matches the actual symptoms a patient is experiencing. Sometimes, patients with severe MRI findings have mild symptoms, and vice versa.\n\nThe purpose of this observational study is to understand the relationship between a patient's clinical symptoms and their MRI results. Researchers want to see if the severity of the spinal damage shown on an MRI can accurately predict how much pain or disability a patient has.\n\nParticipants in this study are adults (ages 18-70) who are already experiencing symptoms of lumbar disc disease and have recently had an MRI. During the study, participants will:\n\n* Complete a questionnaire about the intensity of their back and leg pain.\n* Fill out a survey about how their back pain affects their daily activities.\n* Undergo a standard physical and neurological examination by a doctor to check their reflexes, muscle strength, and sensation.\n\nResearchers will then compare these physical examination and questionnaire results with the detailed findings from the patient's MRI scans. The goal of this research is to improve diagnostic accuracy and help doctors make better, more personalized treatment decisions for future patients with lower back pain.",[32,33,34,35],"Lumbar Disc Disease","Low Back Pain","Lumbar Disc Herniation","Lumbosacral Radiculopathy",[37,38,39,40,41,42,43],"Magnetic Resonance Imaging (MRI)","Visual Analog Scale (VAS)","Oswestry Disability Index (ODI)","Pfirrmann Grading System","Nerve Root Compression","Spinal Canal Stenosis","Disc Degeneration","NOT_YET_RECRUITING","2026-04-01",{"date":47,"type":48},"2026-04-08","ACTUAL",{"date":50,"type":28},"2026-04",{"date":52,"type":28},"2027-05",{"name":5,"class":6}]