[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572214":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":26,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":26,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Mansoura University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MTA Pulpotomy without Photobiomodulation","ACTIVE_COMPARATOR","Participants will receive MTA (Mineral Trioxide Aggregate) pulpotomy as a standard treatment without the application of photobiomodulation (low-level laser therapy).",[13],"Procedure: MTA Pulpotomy without photobiomodulation",{"label":15,"type":16,"description":17,"interventionNames":18},"MTA Pulpotomy with Photobiomodulation","EXPERIMENTAL","Participants will receive MTA (Mineral Trioxide Aggregate) pulpotomy treatment enhanced with photobiomodulation (low-level laser therapy). The laser will be applied to pulp stumps before the placement of MTA to promote healing and reduce inflammation.\n\nThese entries should resolve the error and align with your protocol.",[19],"Procedure: MTA Pulpotomy with Photobiomodulation (LLLT)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","MTA Pulpotomy without photobiomodulation","This intervention involves the application of Mineral Trioxide Aggregate (MTA) to the pulp chamber after the removal of the coronal pulp tissue in first permanent molars with irreversible pulpitis. The procedure is performed without the use of photobiomodulation (low-level laser therapy). The MTA is placed as a seal to preserve the vitality of the remaining radicular pulp.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"MTA Pulpotomy with Photobiomodulation (LLLT)","This intervention combines MTA pulpotomy with photobiomodulation (low-level laser therapy). After performing the MTA pulpotomy, low-level laser therapy is applied to the pulp stumps to reduce inflammation, promote healing, and modulate pain. The laser therapy uses specific wavelengths of light to stimulate cellular activity and enhance the regeneration of pulp tissue.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"peter samir abdelshahed, assistant lecture","CONTACT","+201141859508","petersamir@mans.edu.eg",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Faculty of Dentistry","RECRUITING","Al Mansurah","Dakahlia Governorate","35516","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.38069,31.03637,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":35,"phoneExt":26,"email":36},"peter samir abdelshahed",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Peter Samir","assistant lecturer","100572214","clinical-and-radiographic-assessment-of-photobiomodulated-mta-pulpotomy-in-immature-first-permanent-molars-with-irreversible-pulpitis-100572214",false,"NCT06730360","Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis","Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis: a Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Children aged 6 to 9 years.\n* Non-contributory medical history (healthy otherwise).\n* Presence of carious first permanent molars with the following characteristics:\n* Deep caries extending to ≥2\u002F3 of dentin.\n* Positive response to cold testing.\n* Clinical diagnosis of irreversible pulpitis (moderate or severe), with or without periapical periodontitis.\n* Restorable tooth.\n* Probing pocket depth and mobility within normal limits.\n* No signs of pulpal necrosis, including sinus tract or swelling.\n\nExclusion Criteria:\n\n* Insufficient bleeding after pulp exposure (indicating necrotic or partially necrotic pulp).\n* Presence of systemic or medical conditions that may contraindicate participation.\n* Teeth with unrestorable structure.\n* Teeth showing signs of pulpal necrosis, such as the presence of a sinus tract or swelling.","ALL","6 Years","9 Years",{"count":70,"type":71},72,"ESTIMATED","INTERVENTIONAL",[74],"NA","This study evaluates the effectiveness of photobiomodulation (PBM) in conjunction with mineral trioxide aggregate (MTA) pulpotomy for treating irreversible pulpitis in immature first permanent molars. PBM, also known as low-level laser therapy (LLLT), is used to enhance healing, reduce inflammation, and manage pain in young teeth. The randomized clinical trial involves 72 children aged 6-9 years, divided into two groups: one receiving MTA pulpotomy alone and the other receiving MTA pulpotomy with PBM. Clinical and radiographic outcomes will be assessed at intervals over 15 months. This research aims to determine the combined therapy's efficacy in improving pulp healing and reducing post-operative discomfort compared to MTA alone.",[77,78],"Dental Caries","Irreversible Pulpitis",[80,81,82,83,84],"Irreversible pulpitis","Immature permanent molars","Vital pulp therapy (VPT)","Mineral trioxide aggregate (MTA)","Photobiomodulation (PBM)","2024-12-12",{"date":87,"type":88},"2024-12-17","ACTUAL",{"date":90,"type":88},"2024-10-10",{"date":92,"type":71},"2026-04-05",{"name":5,"class":6},1]