[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527289":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":28,"locations":36,"responsibleParty":54,"collaborators":10,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":76,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Guangzhou 8th People's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cytokine Adsorption Combined with Standard Treatment Group",null,"This group receives cytokine adsorption combined with standard treatment, specifically via hemoperfusion using the standard 211 protocol: two hemoperfusions within the first 24 hours, followed by one hemoperfusion daily. Each hemoperfusions session does not exceed 6 hours, lasting a total of 3 days. All patients also undergo blood perfusion treatment with the addition of a plasma separator.",[13],"Device: Cytokine Adsorption",{"label":15,"type":10,"description":16,"interventionNames":10},"Standard Treatment Group","This group receives only standard treatment . Standard treatment includes symptomatic supportive therapy, etiological therapy, fluid resuscitation, application of vasopressors, and non-invasive or invasive ventilation therapy.",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DEVICE","Cytokine Adsorption","During treatment with cytokine adsorption cartridge, the patient's blood is passed through these cartridges, which contain substances that can adsorb specific cytokines. Excess cytokines are captured and removed by these substances, and then the cleansed blood is returned to the patient's body.",[9],[24],{"name":25,"affiliation":26,"role":27},"Linghua Li, PhD","Guangzhou Eighth People's Hospital","STUDY_CHAIR",[29,33],{"name":25,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","+862083710825","llheliza@126.com",{"name":34,"role":30,"phone":31,"phoneExt":10,"email":35},"Yaozu He, MD","hyzdyl99@163.com",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Guangzhou Eighth People's Hospital, Guangzhou Medical University","RECRUITING","Guangzhou","Guangdong","510060","China","CN",{"type":46,"coordinates":47},"Point",[48,49],113.25,23.11667,{"lat":49,"lon":48},[52,53],{"name":25,"role":30,"phone":31,"phoneExt":10,"email":32},{"name":34,"role":30,"phone":31,"phoneExt":10,"email":35},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Linghua LI","Chief physician","100527289","clinical-application-of-cytokine-adsorption-technique-in-aids-patients-with-severe-pneumonia-andor-septic-shock-100527289",false,"NCT06145828","Clinical Application of Cytokine Adsorption Technique in AIDS Patients With Severe Pneumonia and\u002For Septic Shock","Clinical Application of Cytokine Adsorption Technology in AIDS Patients With Severe Pneumonia and\u002For Septic Shock: An Observational Study.","Inclusion Criteria:\n\n1. Confirmed HIV infection;\n2. Progression to AIDS stage: CD4+ count \\\u003C200 cells\u002Ful and\u002For occurrence of AIDS opportunistic infections;\n3. Age between 18 and 65 years;\n4. Meeting the diagnosis of severe pneumonia or septic shock:\n\n   1. The criteria for severe pneumonia diagnosis refer to the 2021 ATS (American Thoracic Society) and IDSA (Infectious Diseases Society of America) guidelines for the treatment of community-acquired pneumonia;\n   2. The criteria for septic shock refer to the Chinese Society of Critical Care Medicine's \"Chinese Guidelines for the Emergency Treatment of Sepsis\u002FSeptic Shock (2018).\n\nExclusion Criteria:\n\n1. Coexisting central nervous system lesions, severe liver disease, or cirrhosis;\n2. Concurrent AIDS-related or unrelated tumors;\n3. Women who are pregnant or breastfeeding;\n4. Severe underlying diseases of the heart, lungs, liver, kidneys, etc.;\n5. Alcohol abuse or drug use;\n6. The researcher believes that the overall condition of the subject affects the evaluation and completion of the trial.","ALL","18 Years","65 Years",{"count":69,"type":70},60,"ESTIMATED","OBSERVATIONAL","Observing the Real-World Application Effectiveness of Cytokine Immune Adsorption Technology in AIDS Patients with Severe Pneumonia or septic shock.",[74,75],"AIDS Pneumonia","Septic Shock",[77,78,75,79],"AIDS","Severe Pneumonia","Cytokine Adsorption Technique","2023-11-17",{"date":82,"type":83},"2023-11-24","ACTUAL",{"date":85,"type":83},"2023-10-23",{"date":87,"type":70},"2027-10-23",{"name":5,"class":6},1]