[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534691":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":31,"locations":40,"responsibleParty":63,"collaborators":66,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":10,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":91,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Jagiellonian University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"J-PET group",null,"The patient is referred for a PET\u002FCT scan, in accordance with recognized indications for examining the brain or the entire body.",[13],"Diagnostic Test: J-PET scan",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","J-PET scan","Diagnostic Test: Positron-Emission Tomography Imaging Examination of radiation distribution in the patient body after completing a routine examination on a PET diagnostic device. J-PET prototype tests will be carried out in patients who have undergone a classic PET examination after administration of \\[18F\\]FDG), \\[68Ga\\]Ga-PSMA, \\[18F\\]choline or \\[68Ga\\]Ga-DOTATATE). The duration of the additional exam will be approximately 20 minutes.",[9],[21,25,28],{"name":22,"affiliation":23,"role":24},"Marta Opalinska, MD, PhD","Department of Endocrinology and Nuclear Medicine, University Hospital in Krakow","PRINCIPAL_INVESTIGATOR",{"name":26,"affiliation":5,"role":27},"Pawel Moskal, PhD","STUDY_CHAIR",{"name":29,"affiliation":5,"role":30},"Ewa Stepien, PhD","STUDY_DIRECTOR",[32,37],{"name":26,"role":33,"phone":34,"phoneExt":35,"email":36},"CONTACT","800-555-5555","+48-126644558","p.moskal@uj.edu.pl",{"name":29,"role":33,"phone":34,"phoneExt":38,"email":39},"+48-126644762","e.stepien@uj.edu.pl",[41],{"facility":23,"status":42,"city":43,"state":10,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Krakow","31-501","Poland","PL",{"type":48,"coordinates":49},"Point",[50,51],19.93658,50.06143,{"lat":51,"lon":50},[54,57,61],{"name":22,"role":33,"phone":55,"phoneExt":10,"email":56},"+48124001455","marta.opalinska@uj.edu.pl",{"name":58,"role":33,"phone":59,"phoneExt":10,"email":60},"Boguslaw Glowa, MD, PhD","+48124001468","glowa@su.krakow.pl",{"name":62,"role":24,"phone":10,"phoneExt":10,"email":10},"Anna Sowa-Staszczak, MD, PhD",{"type":24,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ewa Stępień, PhD","Head of Department of Medical Physics, Institute of Physics",[67],{"name":68,"class":6},"University Hospital in Krakow","100534691","clinical-application-of-the-j-pet-scanner-prototype-100534691",false,"NCT06242119","Clinical Application of the J-PET Scanner Prototype","Clinical Use of a J-PET Scanner Prototype Made of Plastic Scintilators","JPET2Clinic","Inclusion Criteria:\n\n* The patient is referred for a PET\u002FCT scan, in accordance with recognized indications for examining the entire body.\n* Age over 18 years\n* Informed, voluntary consent to participate in the study\n\nExclusion Criteria:\n\n* Pregnant women, breastfeeding women\n* People with a previously diagnosed allergy to radiopharmaceuticals\n* Age under 18 years\n* Lack of cooperation with the patient\n* Lack of informed consent to participate in the study","ALL","18 Years",{"count":80,"type":81},25,"ESTIMATED","OBSERVATIONAL","Positron emission tomography (PET), an advanced diagnostic imaging technique, exploits the annihilation of positrons (e+) to delineate pathological alterations within diseased tissues. Integral to PET scanners are detector systems that transform gamma photons into fluorescent photons, thereby gleaning insights into the energy, time, and spatial distribution of gamma photons emanating from positron-emitting radiopharmaceuticals. Conventional PET scanners, bear a significant financial burden primarily due to their reliance on LSO (lutetium oxyorthosilicate) or LYSO (lutetium yttrium oxyorthosilicate) scintillation crystals. The exorbitant cost and limited availability of these crystal scintillators impede the widespread adoption of PET scanners. In a departure from conventional PET technology, the prototype J-PET scanner employed in this trial employs plastic scintillators, characterized by unique physical properties. This prototype is further equipped with bespoke software enabling three-photon imaging based on the annihilation of ortho-positronium (o-Ps) generated within diseased tissue. This study delves into the clinical applicability of PET scanners employing plastic scintillators, particularly investigating the feasibility of PET imaging using plastic scintillators where gamma quanta interact by mechanisms other than the photoelectric effect. Furthermore, this study endeavors to contemporaneously acquire and analyze data related to the lifetime of ortho-positronium (o-P) atoms emanating from routine radiopharmaceuticals. Additionally, it seeks to validate the utilization of a novel diagnostic indicator, termed the \\"positron biomarker,\\" through a prospective study, comparing its efficacy to conventional diagnostic PET scanning methodologies.",[85,86,87,88,89,90],"Prostate Cancer","Prostatic Hyperplasia","Prostatic Neoplasms","Prostate Cancer Metastatic","Neuroendocrine Tumors","Neuroendocrine Carcinoma",[92,93,94,95,96,97],"positronium","PET","[18F]FDG","[18F]choline","[68Ga]Ga-DOTA-TATE","[68Ga]Ga-PSMA","2025-02-17",{"date":100,"type":101},"2025-02-19","ACTUAL",{"date":103,"type":101},"2024-03-07",{"date":105,"type":81},"2025-10-30",{"name":5,"class":6},1]