[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559700":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":38,"centralContacts":44,"locations":53,"responsibleParty":79,"collaborators":30,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":30,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":30,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":68,"whyStopped":30,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","ACTIVE_COMPARATOR","absorbable gelatin sponge",[13],"Other: control group",{"label":15,"type":10,"description":16,"interventionNames":17},"Platelet-rich fibrin (PRF) group","Platelet-rich fibrin (PRF) is a biomaterial derived from the patient's own blood, utilized primarily in regenerative medicine and surgery due to its rich content of growth factors and its ability to promote healing.",[18],"Other: Platelet-rich fibrin (PRF)",{"label":20,"type":21,"description":22,"interventionNames":23},"Albumin Platelet Rich- Fibrin (Alb-PRF) group:","EXPERIMENTAL","Albumin Platelet-Rich Fibrin (Alb-PRF) is an innovative biomaterial that combines the regenerative properties of platelet-rich fibrin (PRF) with the structural and functional benefits of albumin. This mixture is designed to enhance tissue healing and regeneration by utilizing autologous blood components.",[24],"Other: Albumin Platelet Rich- Fibrin",[26,31,34],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"control group","An absorbable gelatin sponge is a sterile hemostatic agent primarily composed of purified porcine-derived gelatin. It is widely utilized in surgical procedures to control bleeding",[9],null,{"type":6,"name":32,"description":16,"armGroupLabels":33,"otherNames":30},"Platelet-rich fibrin (PRF)",[15],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":30},"Albumin Platelet Rich- Fibrin","is an innovative biomaterial that combines the regenerative properties of platelet-rich fibrin (PRF) with the structural and functional benefits of albumin. This mixture is designed to enhance tissue healing and regeneration by utilizing autologous blood components.",[20],[39,42],{"name":40,"affiliation":5,"role":41},"Enji Mahmoud, Phd","STUDY_DIRECTOR",{"name":43,"affiliation":5,"role":41},"Sarah Elbanna, Phd",[45,50],{"name":46,"role":47,"phone":48,"phoneExt":30,"email":49},"Samar Idris Hamadelnil Idris Samar Idris, master","CONTACT","01273600331","samar.Idris@dentistry.cu.edu.eg",{"name":51,"role":47,"phone":52,"phoneExt":30,"email":49},"samar idris","01553172036",[54,67,72],{"facility":5,"status":55,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":30},"NOT_YET_RECRUITING","Cairo","Cairo Governorate","12613","Egypt","EG",{"type":62,"coordinates":63},"Point",[64,65],31.24967,30.06263,{"lat":65,"lon":64},{"facility":5,"status":68,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":69,"geoPoint":71,"contacts":30},"RECRUITING",{"type":62,"coordinates":70},[64,65],{"lat":65,"lon":64},{"facility":5,"status":68,"city":73,"state":57,"zip":74,"country":59,"countryCode":60,"cosmosGeoPoint":30,"geoPoint":30,"contacts":75},"Giza","12567",[76],{"name":77,"role":47,"phone":78,"phoneExt":30,"email":49},"Idris","127300331",{"type":80,"investigatorFullName":81,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Samar Idris Hamelin Idris","Principal Investigator","100559700","clinical-comparison-of-alb-prf-vs-prf-on-postoperative-morbidity-following-fgg-harvesting-100559700",false,"NCT06567548","Clinical Comparison of Alb-PRF vs PRF on Postoperative Morbidity Following FGG Harvesting","Clinical Comparison of Albumin Platelet Rich- Fibrin (Alb-PRF) Versus Platelet-rich Fibrin (PRF) on Postoperative Morbidity Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Patients in need of free gingival graft\n2. Medically free patients\n3. Adult patients above 18 years old.\n4. Patients accepting a 1-month follow-up period (cooperative patients).\n5. Patients who will provide an informed consent.\n\nExclusion Criteria:\n\n1. Smokers\n2. Pregnant and lactating women\n3. Patients with poor oral hygiene\n4. Patients who had previous periodontal surgery in the area of interest",true,"ALL","18 Years","70 Years",{"count":95,"type":96},39,"ESTIMATED","INTERVENTIONAL",[99],"NA","Clinical Comparison of Albumin Platelet Rich- Fibrin (Alb- PRF) versus Platelet-rich fibrin (PRF) on Postoperative Morbidity Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial(RCT)\n\nStudy settings:\n\n* The study will be conducted in the Oral Medicine and Periodontology department, Faculty of Dentistry - Cairo University, Egypt.\n* Patients will be selected from the Department of Oral Medicine and Periodontology-Cairo University outpatient clinic.\n\nExpected Duration of Participation and Number of Participants: Research Duration: 28 days Number of Participants: 39 volunteers\n\nWork Plan:\n\nDuring the first visit, preoperative photographs will be taken. Then, participants will be randomly assigned (using a website) into three groups:\n\nGroup A: Application of Alb-PRF at the donor site of the free gingival graft. Group B: Application of PRF at the donor site of the free gingival graft. Control: Application of Gelatin Sponge at the donor site.\n\n* 10 ml of venous blood will be drawn from the patient to prepare Alb-PRF and PRF membranes for placement at the donor site.\n* The membrane or gelatin sponge will be placed at the donor site and sutured.\n\nPostoperative Protocol:\n\nAfter surgery, patients will be instructed to take 600 mg of ibuprofen, and 0.12% chlorhexidine gluconate mouthwash for two weeks postoperatively.\n\nAnalgesics will be recommended only if there is pain, and no antibiotics will be prescribed.\n\nPatients will receive verbal and written dietary advice postoperatively. They will be encouraged to avoid heat sources and adhere to a diet of cold and soft foods.\n\nCleaning the adjacent palatal side of the surgical site will be prohibited to avoid irritation, while gentle cleaning will be recommended after dressing removal.\n\nIn case of postoperative problems such as unusual bleeding or gum recession, patients will be provided with contact information for their physician for early intervention.\n\nDuring Visual Analog Scale (VAS) pain recording, patients will be instructed only to describe pain from the palate and to track additional analgesic intake and consumed tablets. Follow-up visits will be scheduled on days 3, 7, 14, 21, and 28 postoperatively.\n\nPostoperative Follow-up:\n\nPalatal sutures will be removed after 7 days post-surgery. On days 14, 21, and 28, wound healing, tissue color match, complete re-epithelialization of the wound, and clinical wound healing area will be monitored.",[102],"Palate; Wound",[104,105,106],"PRF","Alb-PRF","FGG","2026-03-23",{"date":109,"type":110},"2026-03-27","ACTUAL",{"date":112,"type":110},"2025-11-27",{"date":114,"type":96},"2027-01-30",{"name":5,"class":6},3]