[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634177":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":39,"centralContacts":43,"locations":52,"responsibleParty":69,"collaborators":26,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":26,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":93,"whyStopped":26,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Universitaire Ziekenhuizen KU Leuven","OTHER",[8,16],{"label":9,"type":6,"description":10,"interventionNames":11},"Responder to conservative treatment","After 4 months of conservative treatment patients come to a follow-up consultation for clinical re-assessment with the respective treating orthopaedic surgeon to review symptoms progress and treatment plan. Based on clinical reassessment and PROMS results participants will be divided into Responder or Non-responder to conservative treatment based on iHOT-33 change and PASS. Responders: continuation of nonoperative care (8-10 sessions).",[12,13,14,15],"Diagnostic Test: Functional lateral x-ray scans","Diagnostic Test: Multi-echo Fast Field Echo (mFFE) MRI","Diagnostic Test: Markerless 3D motion capture","Diagnostic Test: Marker-based 3D motion capture (optional)",{"label":17,"type":6,"description":18,"interventionNames":19},"Non-responder to conservative treatment","After 4 months of conservative treatment patients come to a follow-up consultation for clinical re-assessment with the respective treating orthopaedic surgeon to review symptoms progress and treatment plan. Based on clinical reassessment and PROMS results participants will be divided into Responder or Non-responder to conservative treatment based on iHOT-33 change and PASS. Non-responders: offered surgery (arthroscopic or mini-open), with full discussion of risks and benefits according to routine practice.",[12,13,14,15],[21,27,31,35],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIAGNOSTIC_TEST","Functional lateral x-ray scans","Functional lateral x-ray scans will be obtained in three postures: standing, relaxed sitting, and deep flexed sitting. This previously validated protocol, provides posture-specific measures of spinopelvic alignment under physiological load and allows to integrate weight-bearing spinopelvic alignment into 3D hip coverage analysis. By extending imaging beyond a femur-centric perspective, this method better reflects the dynamic, multi-regional nature of FAIS.",[17,9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Multi-echo Fast Field Echo (mFFE) MRI","A multi-echo Fast Field Echo (mFFE) MRI will be acquired to generate highcontrast, bone-like images without ionizing radiation. The imaging sequence can be readily implemented on standard 1.5T and 3T MRI scanners available at the collaborating sites. An in-house pipeline will enable automated 3D segmentation of the lumbar spine, pelvis, acetabulum, proximal femur and condyles.",[17,9],{"type":22,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"Markerless 3D motion capture","Participants will complete markerless 3D motion capture during three hip-hinge tasks: deep squat, sumo squat, and Romanian deadlift (20% body weight). Lumbar, pelvic and hip movements will be measured in all three planes. Data will be recorded using two research-dedicated iPads running the movement tracking software.",[17,9],{"type":22,"name":36,"description":37,"armGroupLabels":38,"otherNames":26},"Marker-based 3D motion capture (optional)","In a subgroup of participants, during three hip-hinge tasks: deep squat, sumo squat, and Romanian deadlift (20% body weight). Lumbar, pelvic, and hip movements will be measured in all three planes using our validated marker-based 3D motion capture system.",[17,9],[40],{"name":41,"affiliation":5,"role":42},"Stijn Ghijselings, Dr.","PRINCIPAL_INVESTIGATOR",[44,48],{"name":41,"role":45,"phone":46,"phoneExt":26,"email":47},"CONTACT","+32 16 33 88 72","stijn.ghijselings@uzleuven.be",{"name":49,"role":45,"phone":50,"phoneExt":26,"email":51},"Anna Tarasiuk","+32 16 33 88 18","orthopedie.research@uzleuven.be",[53],{"facility":5,"status":26,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Leuven","Vlaams-Brabant","3000","Belgium","BE",{"type":60,"coordinates":61},"Point",[62,63],4.70093,50.87959,{"lat":63,"lon":62},[66,67,68],{"name":41,"role":45,"phone":46,"phoneExt":26,"email":47},{"name":49,"role":45,"phone":50,"phoneExt":26,"email":51},{"name":41,"role":42,"phone":26,"phoneExt":26,"email":26},{"type":70,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100634177","clinical-decision-making-in-fais-100634177",false,"NCT07536295","Clinical Decision-Making in FAIS","Optimizing Treatment Pathway and Clinical Desicion-making in Young Adults With Femoroacetabular Impingement Syndrome","CDM-FAIS","Inclusion Criteria:\n\n1. Voluntary written informed consent of the participant or their legally authorized representative has been obtained prior to any screening procedures\n2. Male or Female, Age 18-35 years inclusive.\n3. First consultation at participating site with clinical diagnosis of FAIS by a hip orthopaedic surgeon, including positive impingement tests and reduced hip ROM in the transverse plane compatible with FAIS.\n4. Radiographic cam and\u002For pincer morphology on standard imaging (e.g. α-angle \\>60°, lateral center-edge angle \\>40°, crossover sign) as per local protocol.\n5. Willingness and ability to participate rehabilitation and complete the recommended physiotherapy sessions and attend scheduled follow-up visits.\n6. Ability to perform basic squat \u002F hip-hinge tasks safely in the motion lab, as judged by the treating clinician.\n\nExclusion Criteria:\n\n1. Previous surgery on the bilareral hip.\n2. History of major hip trauma or pediatric hip disease (e.g. Slipped capital femoral epiphysis, Perthes disease).\n3. Developmental dysplasia (lateral center-edge ≤20°) or other severe structural deformity incompatible with the standard FAIS pathway.\n4. Radiographic signs of hip degeneration (Tönnis grade \\>2).\n5. Other musculoskeletal conditions that significantly interfere with assessments (e.g. symptomatic lumbar disc disease, severe knee pathology, recent adductor muscle pathology).\n6. Contraindications to MRI (e.g. non-MRI compatible pacemaker or implant, severe claustrophobia not manageable with standard care).\n7. Contraindications to X-ray or MRI related to pregnancy: known pregnancy at any time, or positive pregnancy test prior to imaging; breastfeeding women will not undergo additional research imaging.\n8. Inability to perform basic squat\u002Fhip-hinge tasks safely (e.g. due to balance, pain or cardiopulmonary limitations).","ALL","18 Years","35 Years",{"count":83,"type":84},60,"ESTIMATED","INTERVENTIONAL",[87],"NA","Femoroacetabular impingement syndrome is increasingly recognized as a contributor to cartilage injury and early hip osteoarthritis. Both structured conservative care and arthroscopic surgery can improve pain and function, but a major unresolved clinical problem is deciding who should continue conservative care and who should escalate to surgery, and when. Evidence indicates that shorter symptom duration before surgery is associated with better long-term improvement, meaning delays may reduce the chance of achieving meaningful recovery. Current decision-making still depends largely on static imaging and passive clinical examination, which do not capture the dynamic, movement-related nature of the condition, while advanced three-dimensional imaging and laboratory motion analysis are not practical for routine clinical monitoring. This study aims to address this gap by developing and validating feasible, clinic-ready dynamic assessment methods and integrating weight-bearing pelvic and spinal alignment with three-dimensional hip modeling to support more objective, individualized, and timely treatment decisions.",[90],"Femoracetabular Impingement",[92],"FAIS","NOT_YET_RECRUITING","2026-05-05",{"date":96,"type":97},"2026-05-06","ACTUAL",{"date":99,"type":84},"2026-07",{"date":101,"type":84},"2029-07",{"name":5,"class":6},1]