[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556587":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":26,"locations":10,"responsibleParty":32,"collaborators":34,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":10,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":10,"overallStatus":58,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":10},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Usual Care",null,"Control group of contemporary encounters where clinical decision support alert is not active. Usual care.",{"label":13,"type":10,"description":14,"interventionNames":15},"Clinical Decision Support (CDS): Opioid transition alert","Encounters where the opioid transition clinical decision support (CDS) alert fired. CDS logic is programmed to fire the alert when a provider places an order for an opioid that will transition the patient from acute to subacute opioid therapy (at 30 days) or from subacute to chronic opioid therapy (at 90 days).",[16],"Other: Opioid Transitions Clinical Decision Support (CDS)",[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Opioid Transitions Clinical Decision Support (CDS)","Clinical decision support in the form of an electronic health record (EHR) integrated, provider-facing alert suggesting (a) the patient is transitioning to a new phase of opioid therapy and (b) the provider should review patient pain data and pain management goals as suggested by Center for Disease Control and Prevention (CDC) guidelines.",[13],[23],{"name":24,"affiliation":5,"role":25},"Jason Hoppe, DO","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Heather Tolle, PhD","CONTACT","303-724-9924","heather.tolle@cuanschutz.edu",{"type":33,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[35,38],{"name":36,"class":37},"National Institutes of Health (NIH)","NIH",{"name":39,"class":37},"National Institute on Drug Abuse (NIDA)","100556587","clinical-decision-support-for-safety-of-opioid-transitions-100556587",false,"NCT06527040","Clinical Decision Support for Safety of Opioid Transitions","Inclusion Criteria: Any primary care encounter where an opioid is prescribed that transitions the patient to a different stage of opioid therapy (acute to subacute after 1 month of opioids; subacute to chronic after 3 months of an opioid)\n\nExclusion Criteria:\n\n* Patients \\\u003C12 and \\>89\n* Patients with active cancer diagnosis in last 1 year\n* Patients with hospice care\u002Fpalliative care order\n* Patients with sickle cell disease diagnosis",true,"ALL","12 Years","89 Years",{"count":51,"type":52},200000,"ESTIMATED","OBSERVATIONAL","The objective of this study is to evaluate the impact of clinical decision support (CDS) alert to notify providers when the opioid prescription being written will result in the patient transitioning into a new phase of opioid therapy. The 2022 CDC clinical practice guideline for prescribing opioids for pain recommends providers reassess patient pain as well as the risks and benefits of opioid therapy before patients transition from acute to subacute treatment (1 month of opioid analgesics) and when patients transition from subacute to chronic opioid treatment (3 months). This study will evaluate a clinical decision support tool identifying patients who will be transitioning between phases as a result of an opioid prescription and suggest a review of patient pain and goals. Primary care providers will be randomized at the clinic location to a control arm or intervention arm. The control arm will not be notified that the prescription transitions the patient to a new phase but will have access to the same patient pain scales and information. The intervention arm will receive a notification of the transition and suggest review of patient needs and encourage documentation. Opioid transition orders and outcomes of patients will be examined based on medical records data collected during routine care.",[56,57],"Medication Abuse","Harm Reduction","NOT_YET_RECRUITING","2026-04-20",{"date":61,"type":62},"2026-04-21","ACTUAL",{"date":64,"type":52},"2026-06",{"date":66,"type":52},"2027-06",{"name":5,"class":6}]