[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561502":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":38,"responsibleParty":53,"collaborators":10,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":10,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Chelyabinsk Regional Clinical Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Allograft tricuspid valve replacement",null,"Patients underwent mitral allograft implantation for primary tricuspid valve disease",[13],"Procedure: tricuspid valve replacement",{"label":15,"type":10,"description":16,"interventionNames":17},"Stented biological tricuspid valve replacement","Patients underwent biological stented valve replacement for primary tricuspid valve disease",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","tricuspid valve replacement","Complete or partial tricuspid valve replacement with mitral allograft\u002F complete tricuspid valve replacement with biological prosthesis",[9,15],[25],{"name":26,"affiliation":27,"role":28},"Yuri Malinovsky, PhD","Department of Cardiac Surgery","STUDY_CHAIR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Mikhail Nuzhdin, PhD","CONTACT","0079068608612","austesla2022@gmail.com",{"name":26,"role":32,"phone":36,"phoneExt":10,"email":37},"0073517493732","mikhailnuzhdin@hotmail.com",[39],{"facility":27,"status":40,"city":41,"state":10,"zip":10,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Chelyabinsk","Russia","RU",{"type":45,"coordinates":46},"Point",[47,48],61.42877,55.1611,{"lat":48,"lon":47},[51],{"name":52,"role":32,"phone":10,"phoneExt":10,"email":10},"Yuri Malinovsky",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mikhail Nuzhdin","Director","100561502","clinical-efficacy-and-long-term-outcomes-of-allograft-versus-stented-biological-prosthesis-for-primary-tricuspid-valve-disease-allotri-100561502",false,"NCT06591000","Clinical Efficacy and Long-term Outcomes of ALLOgraft Versus Stented Biological Prosthesis for Primary TRIcuspid Valve Disease (ALLOTRI)","Clinical Efficacy and Long-term Outcomes of Allograft Versus Stented Biological Prosthesis for Primary Tricuspid Valve Disease","Inclusion Criteria:\n\n* Patients with primary tricuspid valve disease and\u002For tricuspid bioprosthetic failure scheduled for tricuspid valve intervention.\n\n  * Intraoperative findings suggested for tricuspid valve replacement rather than repair.\n\nExclusion Criteria:\n\n* Pregnancy\n\n  * Confirmed active drug addiction\n  * Progressive HIV-infection\n  * HIV-infected patients with CD4-cells count less than 250\n  * Patients with secondary tricuspid valve pathology (left-sided valve disease)\n  * LV Ejection fraction less than 40%","ALL","18 Years","70 Years",{"count":68,"type":69},56,"ESTIMATED","OBSERVATIONAL","The aim of the study is to evaluate early safety, clinical efficacy and long-term outcomes of mitral allografts and stented biological prosthesis in tricuspid valve replacement for primary tricuspid valve diseases.",[73,74,75],"Allograft","Bioprosthesis","Tricuspid Valve Disease","2024-09-07",{"date":78,"type":79},"2024-09-19","ACTUAL",{"date":81,"type":79},"2016-01-14",{"date":83,"type":69},"2025-06-14",{"name":5,"class":6},1]