[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552025":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":26,"responsibleParty":45,"collaborators":26,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":26,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":76,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":26},{"fullName":5,"class":6},"First Affiliated Hospital of Xinjiang Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Self-adhesive silicone gel waterproof dressing group","EXPERIMENTAL","Self-adhesive silicone gel waterproof dressing is used after artificial joint replacement surgery",[13],"Device: Self-adhesive silicone gel waterproof dressing",{"label":15,"type":16,"description":17,"interventionNames":18},"Sterile gauze dressing group","ACTIVE_COMPARATOR","Sterile gauze dressing is used after artificial joint replacement surgery",[19],"Device: Sterile gauze dressing",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Self-adhesive silicone gel waterproof dressing","Self-adhesive silicone gel waterproof dressing is used after artificial joint replacement surgery.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sterile gauze dressing","Sterile gauze dressing is used after artificial joint replacement surgery.",[15],[32],{"name":33,"affiliation":34,"role":35},"Li Cao","The first affliated hospital, Xinjiang medical university","STUDY_CHAIR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Long Hua","CONTACT","+8615099182364","hualong_xmu@163.com",{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},"+8613909915960","xjbone@sina.com",{"type":46,"investigatorFullName":38,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100552025","clinical-efficacy-of-self-adhesive-silicone-gel-waterproof-dressings-versus-conventional-dressings-in-the-healing-of-incisions-after-total-joint-arthroplasty-100552025",false,"NCT06467721","Clinical Efficacy of Self-adhesive Silicone Gel Waterproof Dressings Versus Conventional Dressings in the Healing of Incisions After Total Joint Arthroplasty","Clinical Efficacy of Self-adhesive Silicone Gel Waterproof Dressings Versus Conventional Dressings in the Healing of Incisions After Total Joint Arthroplasty: a Prospective, Randomized Controlled Trial Study","Yes","Inclusion Criteria:\n\n1. Age ≥18 years old, gender is not limited;\n2. Meet the diagnostic criteria for artificial joint replacement;\n3. Initial joint replacement surgery;\n4. Voluntary and signed informed consent.\n\nExclusion Criteria:\n\n1. Allergic to self-adhesive silicone rubber waterproof dressing;\n2. Patients with severe knee joint infection who cannot undergo artificial joint replacement;\n3. Progressive renal insufficiency (stage 4 and above) or glomerular filtration rate less than 30ml\u002Fmin;\n4. periprosthesis infection after multiple joint replacement;\n5. Active infection at the site of intravenous or joint injection;\n6. long-term use of anticoagulants or antiplatelet drugs due to other diseases;\n7. Have sepsis or positive blood culture within the last 30 days;\n8. Radiotherapy and chemotherapy are required due to neoplastic diseases;\n9. Receiving systemic glucocorticoid therapy (prednisone \\> 10mg\u002F day or equivalent hormone medication);\n10. severe immunodeficiency diseases (such as stage 3 HIV, sickle cell anemia, splenectomy, etc.);\n11. Have a history of drug abuse;\n12. Treatment of bone marrow or other transplants with immunosuppressive drugs;\n13. Pregnant, parturient and lactating women;\n14. Participating in other clinical trials;\n15. Researchers believe that other reasons are not appropriate for clinical trial participants.",true,"ALL","18 Years","80 Years",{"count":61,"type":62},600,"ESTIMATED","INTERVENTIONAL",[65],"NA","The efficacy of using self-adhesive silicone gel waterproof dressings versus conventional gauze dressings for recovery after total joint arthroplasty (TJA) remains unclear. In our study, we conducted a prospective, randomized controlled trial to compare these two types of dressings. Patients were divided into two groups following TJA, and we collected primary outcome measures such as skin infection rate and re-operation rate. Additionally, we gathered blood inflammatory indicators, including C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), to evaluate the effectiveness of the two treatments. Finally, we perform one year follow up including REEDA score, MSS score to evaluate the recovery of the skin.",[68,69,70],"Self-adhesive Silicone Gel Waterproof Dressing","Gauze Dressing","Total Joint Arthroplasty",[72,73,74,75],"self-adhesive silicone gel waterproof dressing","gauze dressing","total joint arthroplasty","RCT","NOT_YET_RECRUITING","2024-06-15",{"date":79,"type":80},"2024-06-21","ACTUAL",{"date":82,"type":62},"2024-08-01",{"date":84,"type":62},"2026-12-31",{"name":5,"class":6}]