[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575613":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":25,"responsibleParty":35,"collaborators":25,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":25,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":25,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":25,"overallStatus":58,"whyStopped":25,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":25},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CAD\u002FCAM milled onlays","ACTIVE_COMPARATOR","CAD\u002FCAM has had a lasting impact on the dental market for decades. Its clinical reliability compared to any other dental material has been well documented. Several clinical studies proved its high clinical performance and survival rate. As CAD\u002FCAM systems have become established in producing indirect restorations, it is considered the gold standard of digital manufacturing technology in dentistry.",[13],"Other: CAD\u002FCam milled onlays",{"label":15,"type":16,"description":17,"interventionNames":18},"3D printed onlays","EXPERIMENTAL","3D-printed restorations have shown several advantages. Some studies have shown that the edge and internal gap values of 3D printing restorations are significantly lower than those of milling restorations.",[19],"Other: 3D printed onlays",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"CAD\u002FCam milled onlays","The digital workflow in dentistry has proven in the past decades to be a time-efficient, multifunctional, effortless, and accessible approach. The inherited shortages milling machines represented by the incapability to produce accurate complex hollow structures may give preference to modern 3D ceramic printing.\n\nComputer-aided-design\u002Fcomputer-aided-manufacturing (CAD\u002FCAM) in dentistry is a digital subtractive approach for manufacturing indirect restorations. Nevertheless, waste materials and milling burs wearing are considered as key disadvantages of CAD\u002FCAM technology, and are the main drive to improve 3D printing technology (additive manufacturing) as the latter has shown considerable efficiency in minimising wasted materials.",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"3D printing technologies are developing more intensively in dentistry as this technology has the capacity to produce shapes or models with high accuracy and in a short time. This method of fabrication takes less time and money and saves on materials compared to CAD\u002FCAM.\n\nAlthough it seems that digital manufacturing technology has made great changes in the restorative dentistry field, this technology is still not fully in use. This is possibly because of the lack of studies and research on this technology, particularly in terms of clinical performance and patient-centred outcomes. 3D printing technologies are novel technologies with a lack of research; therefore, the processing of 3D printing materials is still controversial.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Nada Sameh assistant lecturer","CONTACT","00201065228277","nada.farouk@dentistry.cu.edu.eg",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Nada Sameh Ahmed Farouk","Principal investigator","100575613","clinical-evaluation-of-3d-printed-versus-cadcam-milled-onlays-100575613",false,"NCT06774560","Clinical Evaluation of 3D Printed Versus CAD\u002FCAM Milled Onlays","Clinical Evaluation of 3D Printed Versus CAD\u002FCAM Milled Onlays Over a Period of One Year: a Randomized Clinical Trial","Inclusion Criteria:\n\nAge: 25-45 years.\n\n* Males or females.\n* Participants with carious vital ower molars indicated for onlay (one or two missing cusps)\n* Patients with at least 20 teeth under occlusion.\n* Good oral hygiene.\n* Co-operative patients approving to participate in the trial.\n* Have sufficient cognitive ability to understand consent procedures.\n\nExclusion Criteria:\n\n* Participants with parafunctional habits or bruxism.\n* Participants with systemic diseases or disabilities that may affect participation.\n* Heavy smoking.\n* Pregnancy.\n* Lack of compliance.\n* Severe or active periodontal disease.\n* Cognitive impairment.","ALL","25 Years","45 Years",{"count":50,"type":51},50,"ESTIMATED","INTERVENTIONAL",[54],"NA","The digital workflow in dentistry has proven in the past decades to be a time-efficient, multifunctional, effortless, and accessible approach. The inherited shortages milling machines represented by the incapability to produce accurate complex hollow structures may give preference to modern 3D ceramic printing.\n\nComputer-aided-design\u002Fcomputer-aided-manufacturing (CAD\u002FCAM) in dentistry is a digital subtractive approach for manufacturing indirect restorations. Nevertheless, waste materials and milling burs wearing are considered as key disadvantages of CAD\u002FCAM technology, and are the main drive to improve 3D printing technology (additive manufacturing) as the latter has shown considerable efficiency in minimising wasted materials.\n\nAlthough additive manufacturing has been known since the 1980s, its application in dentistry is relatively new and not fully studied with limited research and in vivo studies on their clinical performance.",[57],"Badly Decayed Molars","NOT_YET_RECRUITING","2025-01-12",{"date":61,"type":62},"2025-01-14","ACTUAL",{"date":64,"type":51},"2025-06-01",{"date":66,"type":51},"2026-12-01",{"name":5,"class":6}]