[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601508":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":44,"centralContacts":49,"locations":54,"responsibleParty":69,"collaborators":33,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":33,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":33,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":33,"overallStatus":56,"whyStopped":33,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Mansoura University","OTHER",[8,14,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"SAP fluoride plus","ACTIVE_COMPARATOR","Participants in this group received P11-4 (Curodont Repair™, Biomedical products for tooth preservation) only at baseline. First, the tooth was completely isolated using rubber dam followed by cleaning of the tooth surface with sodium hypochlorite 2% for 20 s, acid etching with phosphoric acid gel 35-37% for 20 s, rinsing and drying.",[13],"Procedure: SAP fluoride plus",{"label":15,"type":10,"description":16,"interventionNames":17},"10% n-HAp","A Low-speed handpiece was used to clean the tooth surface with fluoride-free pumice (Pumice powder extra fine, SSWhite, Rio de Janeiro, Brazil) after tooth isolation, rinsing, and drying. after that the material was applied",[18],"Procedure: 10% n-HAp.",{"label":20,"type":10,"description":16,"interventionNames":21},"10% n-BAG.",[22],"Procedure: 10% n-BAG.",{"label":24,"type":10,"description":25,"interventionNames":26},"Flour Protector S","The teeth were dried and a very thin coat of the varnish was applied and allowed to dry for 20 s.",[27],"Procedure: Flour Protector S",[29,34,38,41],{"type":30,"name":9,"description":31,"armGroupLabels":32,"otherNames":33},"PROCEDURE","The agent was applied by removing the safety clip, activating the applicator and squeezing out the sponge above the lesion and the solution was left to diffuse for 5 min.the patients were instructed to eat only soft foods and avoid hot liquids for two hours. Also, they were educated and motivated about the importance of oral hygiene.",[9],null,{"type":30,"name":35,"description":36,"armGroupLabels":37,"otherNames":33},"10% n-HAp.","the pastes were applied using micro brushes. The excess was removed after four minutes with a cotton swab. The subjects were advised not to drink or eat for 30 minutes after the treatment. The treatment was applied once every week for a period of four weeks.they instructed to adhere to oral hygiene measures.",[15],{"type":30,"name":20,"description":39,"armGroupLabels":40,"otherNames":33},"the pastes were applied using micro brushes. The excess was removed after four minutes with a cotton swab. The subjects were advised not to drink or eat for 30 minutes after the treatment. The treatment was applied once every week for a period of four weeks. patients instructed to adhere to oral hygiene measures.",[20],{"type":30,"name":24,"description":42,"armGroupLabels":43,"otherNames":33},"After application of varnish, the patient was instructed to avoid abrasive diet for the rest of the day and not brush or floss until the next morning. The treatment was done at baseline and after 6 months.",[24],[45],{"name":46,"affiliation":47,"role":48},"Tarek A Arisha, Ass Lecturer","Faculty of Dentistry, Mansoura University, Egypt","PRINCIPAL_INVESTIGATOR",[50],{"name":46,"role":51,"phone":52,"phoneExt":33,"email":53},"CONTACT","01063912693","tarekadel@mans.edu.eg",[55],{"facility":47,"status":56,"city":57,"state":33,"zip":33,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"RECRUITING","Al Mansurah","Egypt","EG",{"type":61,"coordinates":62},"Point",[63,64],31.38069,31.03637,{"lat":64,"lon":63},[67],{"name":68,"role":51,"phone":52,"phoneExt":33,"email":53},"Tarek A Arisha, Ass lecturer",{"type":70,"investigatorFullName":33,"investigatorTitle":33,"investigatorAffiliation":33,"oldNameTitle":33,"oldOrganization":33},"SPONSOR","100601508","clinical-evaluation-of-remineralizing-potential-of-remineralizing-agents-on-wsls-managment-100601508",false,"NCT07111403","Clinical Evaluation of Remineralizing Potential of Remineralizing Agents on WSLs Managment","Remineralization Potential of Different Remineralizing Agents on Initial Enamel Caries: Laboratory Evaluations and Two-year Randomized Clinical Trial","Inclusion Criteria:\n\n* Participants should have at least one visible initial enamel caries in the permanent teeth\n* Only lesions with ICDAS II score of 1 or 2 could be included\n* The patients must have good oral hygiene\n\nExclusion Criteria:\n\n* patients receiving tetracyclines, any other medication known to stain teeth - Patients had fluoride application less than 3 months before the study\n* Teeth which have microcavities or dentinal involvement due to loss of enamel - Teeth that have discoloration, enamel hypoplasia or fluorosis.","ALL","14 Years","26 Years",{"count":82,"type":83},120,"ESTIMATED","INTERVENTIONAL",[86],"NA","To evaluate and compare the clinical effect of four different remineralizing agents on initial enamel caries after a two years follow up.",[89,90],"Initial Dental Caries","White Spot Lesion of Tooth","2025-08-07",{"date":93,"type":94},"2025-08-13","ACTUAL",{"date":96,"type":94},"2024-09-10",{"date":98,"type":83},"2026-09-17",{"name":5,"class":6},1]