[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584024":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":30,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":10,"maxAge":60,"enrollmentInfo":61,"targetDuration":64,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"primary headache",null,"Subjects who are younger than 65 years old and meet the diagnostic criteria for relevant primary headaches (such as tension-type headache, migraine, cluster headache, trigeminal autonomic cephalalgia, etc.) in the third edition of the International Classification of Headache Disorders (ICHD-3).",[13],"Combination Product: Disease education, pharmacological treatment, Non-pharmacological treatment",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"COMBINATION_PRODUCT","Disease education, pharmacological treatment, Non-pharmacological treatment","Disease education: Provide patients with education on knowledge related to primary headache, including the causes, pathogenesis, symptoms, treatment methods, and preventive measures of headache, etc., to help patients better understand their own diseases and improve their self-management ability.\n\nNon-pharmacological treatment: Although specific non-pharmacological treatment methods are not elaborated in detail in the research protocol, they may include psychotherapy, physical therapy, etc. For example, biofeedback therapy, relaxation training, transcranial magnetic stimulation, etc. These can all be recorded as possible intervention measures.\n\nPharmacological treatment: Record the medications used for the treatment of acute episodes and preventive treatment by patients during the research process, including the types of medications, dosages, frequency of use, etc. For instance, non-steroidal anti-inflammatory drugs and triptan drugs used during acute episodes, and β-blockers.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Yamei Tang, MD, PhD","CONTACT","86-13556001992","tangym@mail.sysu.edu.cn",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Yi Li, MD, PhD","86-15018761512","eleam2002@163.com",[31],{"facility":32,"status":10,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University","Guangzhou","Guangdong","510000","China","CN",{"type":39,"coordinates":40},"Point",[41,42],113.25,23.11667,{"lat":42,"lon":41},[45,46,47],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},{"name":22,"role":48,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":48,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Yamei Tang","Professor and Associate Dean","100584024","clinical-features-and-current-treatment-of-primary-headache-100584024",false,"NCT06883955","Clinical Features and Current Treatment of Primary Headache","Prospective Cohort Study of the Clinical Features and Current Treatment of Primary Headache","Inclusion Criteria:\n\n1. Age is less than 65 years old.\n2. Meets the diagnostic criteria for relevant primary headaches (such as tension-type headache, migraine, cluster headache, trigeminal autonomic cephalalgia, etc.) in the third edition of the International Classification of Headache Disorders (ICHD - 3).\n3. Is willing and able to participate throughout the entire study period and sign the informed consent form.\n4. Has the ability to complete the \"Headache Diary\" independently or with the help of a guardian.\n\nExclusion Criteria:\n\n1. Secondary headache\n2. High - risk populations, such as those with severe heart disease, impaired liver and kidney function, malignant tumors, etc.\n3. Patients with mental illness, cognitive impairment, or those who are unable to cooperate with the research requirements\n4. History of intracranial lesions or other nervous system diseases (including stroke, epilepsy, etc.)","ALL","65 Years",{"count":62,"type":63},2000,"ESTIMATED","60 Years","OBSERVATIONAL","This study is a prospective, observational cohort study. The plan of this study is to consecutively enroll 2,000 primary headache patients who meet the inclusion criteria from the neurology outpatient department and inpatient department of Sun Yat-sen Memorial Hospital, Sun Yat-sen University. Basic clinical data registration, various scale evaluations, cranial imaging examinations, and collection of blood and fecal biological samples will be completed. During the 10-year follow-up plan, systematic clinical evaluations of the disease severity, diagnosis and treatment, living ability and health status of patients will be carried out regularly every 6 - 12 months. Imaging and other functional evaluations will be conducted when necessary. Data collection includes:\n\nDemographic data (including age, gender, education, ethnicity, marital status, occupation, etc.); General clinical data (past medical history, medication history, personal history, menstrual and childbearing history, family history, etc.); Clinical data of primary headache: headache frequency, duration, severity (Numeric Rating Scale for pain, NRS), headache-related medication use, drug efficacy and side effects; Scale evaluations: MIDAS, HIT-6, BPI, MSQ, ADL, CDR, PGIC, CGIC, PHQ-4, mTOQ-4, ASC-12, MIBS-4, HARDSHIP, WHO-QOL BREF, HAMD, HAMA, TNQ; Records of neurological imaging examinations, blood sample and fecal sample collection.",[68],"Primary Headache",[9,70,71,72],"prospective cohort study","clinical features","current treatment","NOT_YET_RECRUITING","2025-03-13",{"date":76,"type":77},"2025-03-19","ACTUAL",{"date":79,"type":63},"2025-03-08",{"date":81,"type":63},"2037-12-31",{"name":5,"class":6},1]