[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100423495":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":54,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":10,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Children's Hospital of Fudan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"sepsis group with CBP",null,"The child with sepsis should be treated with CBP， but could not receive this treatment for various reasons",[13],"Procedure: CBP",{"label":15,"type":10,"description":16,"interventionNames":10},"sepsis group without CBP","The child with sepsis should be treated with CBP and received this treatment",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"PROCEDURE","CBP","continuous blood purification can prevent or treat fluid overload in children with septic shock or other sepsis-associated organ dysfunction who are unresponsive to fluid restriction and diuretic therapy management of septic AKI patients, particularly those with hemodynamic instability or fluid overload. Also, it can remove cytokines",[9],[24],"traditional therapy",[26],{"name":27,"affiliation":5,"role":28},"Lu guoing","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"YING JIAYUN","CONTACT","18817583962","jiayundoctor@163.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Children'S Hospital of Fudan University","RECRUITING","Shanghai","Shanghai Municipality","201102","China","CN",{"type":45,"coordinates":46},"Point",[47,48],121.45806,31.22222,{"lat":48,"lon":47},[51],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},{"type":53,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[55,57,59],{"name":56,"class":6},"Shanghai Children's Hospital",{"name":58,"class":6},"Shanghai Children's Medical Center",{"name":60,"class":6},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","100423495","clinical-features-and-outcomes-of-cbp-versus-non-cbp-in-septic-children-100423495",false,"NCT04794595","Clinical Features and Outcomes of CBP Versus Non-CBP in Septic Children","Clinical Features and Outcomes of Continuous Blood Purification Versus Non-continuous Blood Purification in Pediatric Patients With Sepsis or Septic Shock","Inclusion Criteria:\n\n* Age of 29d to 18 years old;\n* Children diagnosed with sepsis requiring blood purification.\n\nExclusion Criteria:\n\n* with a history of a duration of PICU stay \\\u003C24 h\n* active bleeding, including cerebral hemorrhage","ALL","28 Days","18 Years",{"count":72,"type":73},90,"ESTIMATED","OBSERVATIONAL","The effect of continuous blood purification (CBP) in children is unclear. Also, the timing of early application is still being explored. In this study, we need to explore the efficacy and the timing of application of CBP in children with sepsis or septic shock.",[77,78],"Sepsis","Children, Only",[80,81,82],"Continuous renal replacement therapy","sepsis","timing","2026-03-13",{"date":85,"type":86},"2026-03-16","ACTUAL",{"date":88,"type":86},"2020-12-01",{"date":90,"type":73},"2026-12-30",{"name":5,"class":6},1]