[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616662":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":11,"centralContacts":35,"locations":41,"responsibleParty":62,"collaborators":11,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":11,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":11,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":11,"overallStatus":86,"whyStopped":11,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Baghdad","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Manual toothbrush","ACTIVE_COMPARATOR",null,[13],"Device: Manual toothbrush",{"label":15,"type":10,"description":11,"interventionNames":16},"Electric toothbrush",[17],"Device: Electric toothbrush",{"label":19,"type":20,"description":11,"interventionNames":21},"AI-based toothbrush","EXPERIMENTAL",[22],"Device: AI toothbrush",[24,29,32],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"DEVICE","AI toothbrush","Smart toothbrush supported with AI applications to improve toothbrushing experience",[19],{"type":25,"name":9,"description":30,"armGroupLabels":31,"otherNames":11},"Manual toothbrush used as a gold standard control",[9],{"type":25,"name":15,"description":33,"armGroupLabels":34,"otherNames":11},"Electric toothbrush as a second control group",[15],[36],{"name":37,"role":38,"phone":39,"phoneExt":11,"email":40},"Buthaina Firas Faisal, BDS","CONTACT","+964 7724597036","buthaina.abd2405@codental.uobaghdad.edu.iq",[42],{"facility":43,"status":11,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"College of Dentistry, University of Baghdad","Baghdad","Al-Rasafa","1011","Iraq","IQ",{"type":50,"coordinates":51},"Point",[52,53],44.40088,33.34058,{"lat":53,"lon":52},[56,60],{"name":57,"role":38,"phone":58,"phoneExt":11,"email":59},"Ali Abbas Abdulkareem","+9647806866717","ali.abbas@codental.uobaghdad.edu.iq",{"name":37,"role":61,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"type":61,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Buthaina Firas Faisal","Researcher","100616662","clinical-microbiological-and-compliance-outcomes-of-ai-based-toothbrushes-in-plaque-induced-gingivitis-100616662",false,"NCT07308522","Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis","Clinical ,Microbiological and Compliance Outcomes of AI-based vs Standard Electric and Manual Toothbrushes in Adults With Plaque-Induced Gingivitis: A 6-Week Randomized Controlled Trial","Inclusion Criteria:\n\n* Participants should be systemically healthy\n* 18 years old, with the presence of ≥ 20 teeth\n* Diagnosed with generalized plaque-induced gingivitis having \\>30% bleeding sites, with probing depths ≤3 mm and intact periodontium\n* Participants with at least secondary school education, who are able to read and understand basic English to follow the app-based toothbrush instructions\n\nExclusion Criteria:\n\n* Participants who using antibiotics or anti-inflammatory medication throughout the investigation or during the previous 3 months prior to the study.\n* Drug-induced gingival enlargement (phenytoin, cyclosporine, calciumchannel blockers).\n* Individuals with periodontitis and healthy periodontium.\n* Mouth breathers .\n* Individuals with severe dental crowding or malalignment that prevents proper toothbrushing.\n* Individuals with heavy calculus.\n* Individuals who smoke or alcoholism.\n* Pregnant, breastfeeding women or those using contraceptive tablets.\n* Individuals with orthodontic devices or removable dentures","ALL","18 Years","35 Years",{"count":76,"type":77},33,"ESTIMATED","INTERVENTIONAL",[80],"NA","Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque. Electric brushes remove more plaque and reduce gingivitis better than manual ones, and users show better periodontal status. App-connected smart brushes and apps aim to improve adherence. Trials increased plaque reduction and brushing time versus manual brushing, but app layers have not clearly beaten standard power brushes, and microbiological outcomes are rarely reported. Xiaomi's AI-based sonic T501 adds pressure sensing, personalised coaching and coverage tracking, whereas the T302 is a simpler non-connected sonic brush. Streptococcus sanguinis is a health-associated early coloniser; its qPCR-measured relative abundance marks a healthy supragingival profile. It is still unclear whether AI guidance adds extra benefit beyond a standard electric brush in adult gingivitis.",[83,84,85],"Plaque Induced Gingivitis","Toothbrushing","Compliance","NOT_YET_RECRUITING","2025-12-13",{"date":89,"type":90},"2025-12-29","ACTUAL",{"date":92,"type":77},"2026-01-01",{"date":94,"type":77},"2026-06-30",{"name":5,"class":6},1]