[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637884":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":22,"locations":10,"responsibleParty":28,"collaborators":30,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":39,"eligibilityCriteria":40,"healthyVolunteers":35,"sex":41,"minAge":42,"maxAge":10,"enrollmentInfo":43,"targetDuration":10,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":52,"overallStatus":56,"whyStopped":10,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":10},{"fullName":5,"class":6},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Prospective Cohort",null,"Prospectively enrolled adult patients with diabetes at baseline undergoing partial, near-total, or total pancreatectomy at the study center.",{"label":13,"type":10,"description":14,"interventionNames":10},"Ambispective Cohort","Patients with diabetes at baseline with retrospective baseline data and prospective postoperative follow-up after pancreatic surgery.",{"label":16,"type":10,"description":17,"interventionNames":10},"Retrospective Cohort","Retrospective cohort of adult patients with diabetes at baseline who underwent pancreatic surgery at the study center.",[19],{"name":20,"affiliation":5,"role":21},"Teresa Mezza","PRINCIPAL_INVESTIGATOR",[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Teresa Mezza, MD, PhD","CONTACT","06 30156664","teresa.mezza@policlinicogemelli.it",{"type":29,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[31],{"name":32,"class":6},"European Foundation for the Study of Diabetes","100637884","clinical-oncological-and-metabolic-effects-of-pancreatic-mass-loss-after-partial-near-total-and-total-pancreatectomy-in-patients-with-preoperative-diabetes-mellitus-100637884",false,"NCT07607912","Clinical, Oncological and Metabolic Effects of Pancreatic Mass Loss After Partial, Near-total and Total Pancreatectomy in Patients With Preoperative Diabetes Mellitus","Clinical, Oncological and Metabolic Effects of Pancreatic Mass Loss After Partial, Near-total and Total Pancreatectomy in Patients With Preoperative Diabetes Mellitus: A Monocentric Ambispective Observational Study","DCP-DM","Inclusion Criteria:\n\n* Adult patients (≥18 years)\n* Diabetes mellitus at baseline\n* Undergoing partial, near-total, or total pancreatectomy at the study center for benign or malignant pancreatic disease\n* Availability of clinical and metabolic follow-up data according to study component\n* Written informed consent for the ambispective and prospective components, where applicable\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Absence of diabetes mellitus at baseline\n* Missing essential clinical data or incomplete follow-up precluding evaluation of study outcomes\n* Severe pre-existing non-oncologic clinical conditions with life expectancy \\\u003C6 months\n* Refusal, withdrawal, or inability to provide informed consent for the ambispective and prospective components, where applicable","ALL","18 Years",{"count":44,"type":45},408,"ESTIMATED","OBSERVATIONAL","This study will examine how removal of part or all of the pancreas affects blood sugar control, metabolism, and clinical outcomes over time.\n\nThe study will include adults with diabetes before surgery who undergo pancreatic surgery as part of routine clinical care at Fondazione Policlinico Universitario A. Gemelli IRCCS.\n\nResearchers will study whether glycemic control worsens after surgery and whether this risk changes according to the type of pancreatic resection. The study will also examine changes in glucose metabolism, and cancer-related outcomes.\n\nInformation from routine clinical care, metabolic tests, imaging, and pancreatic tissue samples collected during surgery may be used for research analyses.",[49,50,51],"Diabetes Mellitus Type 2","Pancreatectomy","Pancreatic Neoplasms",[49,53,54,55,50],"Metabolism","Beta Cells Function","Glycemic Control","NOT_YET_RECRUITING","2026-05-21",{"date":59,"type":60},"2026-05-26","ACTUAL",{"date":62,"type":45},"2026-05",{"date":64,"type":45},"2041-05",{"name":5,"class":6}]