[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562179":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":10,"centralContacts":53,"locations":63,"responsibleParty":83,"collaborators":10,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":10,"eligibilityCriteria":91,"healthyVolunteers":87,"sex":92,"minAge":93,"maxAge":10,"enrollmentInfo":94,"targetDuration":10,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":101,"overallStatus":106,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University","OTHER",[8,14,19,24,29],{"label":9,"type":10,"description":11,"interventionNames":12},"Anterolateral thigh flap group",null,"Oral squamous cell carcinoma patients received the reconstruction with anterolateral thigh flaps after tumor resection",[13],"Procedure: Anterolateral thigh flap reconstruction surgery",{"label":15,"type":10,"description":16,"interventionNames":17},"Forearm flap group","Oral squamous cell carcinoma patients received the reconstruction with forearm flaps after tumor resection",[18],"Procedure: Forearm flap reconstruction surgery",{"label":20,"type":10,"description":21,"interventionNames":22},"Latissimus dorsi flap group","Oral squamous cell carcinoma patients received the reconstruction with latissimus dorsi flaps after tumor resection",[23],"Procedure: Forearm flaps reconstruction surgery",{"label":25,"type":10,"description":26,"interventionNames":27},"Fibula flap group","Oral squamous cell carcinoma patients received the reconstruction with Fibula flaps after tumor resection",[28],"Procedure: Fibula flap reconstruction surgery",{"label":30,"type":10,"description":31,"interventionNames":32},"Thoracodorsal artery perforator flap group","Oral squamous cell carcinoma patients received the reconstruction with Thoracodorsal artery perforator flaps after tumor resection",[33],"Procedure: Thoracodorsal artery perforator flap reconstruction surgery",[35,40,43,46,50],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":10},"PROCEDURE","Thoracodorsal artery perforator flap reconstruction surgery","Oral squamous cell carcinoma patients underwent reconstruction with thoracodorsal artery perforator (TDAP) flaps following tumor resection.",[30],{"type":36,"name":41,"description":16,"armGroupLabels":42,"otherNames":10},"Forearm flaps reconstruction surgery",[20],{"type":36,"name":44,"description":11,"armGroupLabels":45,"otherNames":10},"Anterolateral thigh flap reconstruction surgery",[9],{"type":36,"name":47,"description":48,"armGroupLabels":49,"otherNames":10},"Fibula flap reconstruction surgery","Oral squamous cell carcinoma patients received the reconstruction with fibula flaps after tumor resection",[25],{"type":36,"name":51,"description":16,"armGroupLabels":52,"otherNames":10},"Forearm flap reconstruction surgery",[15],[54,59],{"name":55,"role":56,"phone":57,"phoneExt":10,"email":58},"Youyuan Wang, MD, Ph.D","CONTACT","+8613631333312","Wangyy78@mail.sysu.edu.cn",{"name":60,"role":56,"phone":61,"phoneExt":10,"email":62},"Liushan Ou, MD","+8681332587","sys_iit@163.com",[64],{"facility":65,"status":10,"city":66,"state":67,"zip":68,"country":69,"countryCode":70,"cosmosGeoPoint":71,"geoPoint":76,"contacts":77},"Sun Yat-sen Memorial Hospital, Sun Yat-sen Univerity","Guangzhou","Guangdong","510120","China","CN",{"type":72,"coordinates":73},"Point",[74,75],113.25,23.11667,{"lat":75,"lon":74},[78,80,81],{"name":55,"role":56,"phone":57,"phoneExt":10,"email":79},"wufan43@mail2.sysu.edu.cnWangyy78@mail.sysu.edu.cn",{"name":60,"role":56,"phone":61,"phoneExt":10,"email":62},{"name":55,"role":82,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":84,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100562179","clinical-outcomes-of-thoracodorsal-artery-flap-in-oral-and-maxillofacial-reconstruction-100562179",false,"NCT06599801","Clinical Outcomes of Thoracodorsal Artery Flap in Oral and Maxillofacial Reconstruction","The Clinical Outcomes of Thoracodorsal Artery Flap in Oral and Maxillofacial Defect Reconstruction: a Retrospective Study","Inclusion Criteria:\n\n1. Patients with oral squamous cell carcinoma who have completed comprehensive imaging examinations before surgery.\n2. Preoperative pathological biopsy confirmed as oral squamous cell carcinoma.\n3. Patients with oral squamous cell carcinoma who have completed comprehensive laboratory tests before surgery.\n4. Patients with oral squamous cell carcinoma who underwent tumor resection and flap reconstruction at our hospital.\n5. Postoperative pathological diagnosis confirmed as oral squamous cell carcinoma.\n6. Patients with oral squamous cell carcinoma who attend follow-up visits at 1, 3, 6, and 12 months post-surgery, completing all clinical examinations and questionnaires.\n\nExclusion Criteria:\n\n1. Patients with oral squamous cell carcinoma who lack imaging data or have artifacts affecting imaging results.\n2. Patients with oral squamous cell carcinoma who have incomplete laboratory test results from our hospital.\n3. Patients with oral squamous cell carcinoma with postoperative pathology that remains unclear or cannot be confirmed as oral squamous cell carcinoma.\n4. Patients with oral squamous cell carcinoma who are unable to attend follow-up visits at 1, 3, 6, and 12 months.\n5. Patients who do not complete the questionnaires as required during follow-up visits.","ALL","18 Years",{"count":95,"type":96},217,"ESTIMATED","OBSERVATIONAL","The goal of this study is to retrospectively compare different types of free flaps to determine the most suitable free flap for functional reconstruction in oral squamous cell carcinoma patients following tumor resection. The main questions it aims to answer are:\n\nDo the clinical characteristics of the thoracodorsal artery perforator flap differ from those of other types of flaps? Does the thoracodorsal artery perforator flap result in better clinical outcomes compared to other types of flaps? After reconstruction with the thoracodorsal artery perforator flap, do patients have better quality of life, speech function and scar healing compared to other types of flaps? Investigators will retrospectively compare the thoracodorsal artery perforator flap with other types of flaps (such as the anterolateral thigh flap, forearm flap, latissimus dorsi flap and fibula flap) to explore the most suitable free flap for facial defect reconstruction in oral squamous cell carcinoma patients.\n\nParticipants are oral squamous cell carcinoma patients who previously underwent facial defect reconstruction with different types of flaps. Participants have completed relevant questionnaires at 1, 3, 6 and 12 months post-surgery. The data will be scored and assessed by the investigators.",[100],"Oral Squamous Cell Carcinoma (OSCC)",[102,103,104,105],"Oral Squamous Cell Carcinoma","thoracodorsal artery perforator flap","quality of life","free flap","NOT_YET_RECRUITING","2024-09-13",{"date":109,"type":110},"2024-09-19","ACTUAL",{"date":112,"type":96},"2024-09-30",{"date":114,"type":96},"2025-09-30",{"name":5,"class":6},1]