[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633296":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":29,"centralContacts":29,"locations":29,"responsibleParty":36,"collaborators":29,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":29,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":29,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":29,"overallStatus":60,"whyStopped":29,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":29},{"fullName":5,"class":6},"Hacettepe University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"bioactive composite","EXPERIMENTAL","Cention Forte Ivoclar Vivadent, Schaan, Liechtenstein",[13],"Device: bioactive composite",{"label":15,"type":10,"description":16,"interventionNames":17},"nanohybrid resin composite","Tetric N-Ceram2 (Ivoclar Vivadent, Schaan, Liechtenstein)",[18],"Device: nanohybrid resin composite",{"label":20,"type":10,"description":21,"interventionNames":22},"bulk-fill resin composite","Tetric N-PowerFill2 (Ivoclar Vivadent, Schaan, Liechtenstein)",[23],"Device: bulk-fill resin composite",[25,30,33],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","bioactive composite restoration",[9],null,{"type":26,"name":15,"description":31,"armGroupLabels":32,"otherNames":29},"nanohybrid resin composite restoration",[15],{"type":26,"name":20,"description":34,"armGroupLabels":35,"otherNames":29},"bulk-fill resin composite restoration",[20],{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Dr. Fatma Dilşad Öz","Prof. Dr.","100633296","clinical-performance-of-three-different-restorative-materials-100633296",false,"NCT07524842","Clinical Performance of Three Different Restorative Materials","Clinical Performance of Three Different Restorative Materials-Nanohybrid, Bulk-fill, and Alkasite-based","Inclusion Criteria:\n\n* age range will be 18 to 65\n* patients should have at least 3 approximal caries lesions require restoration\n* healthy periodontal status\n* a good likelihood of recall availability\n\nExclusion Criteria:\n\n* poor gingival health\n* adverse medical history\n* potential behavioral problems",true,"ALL","18 Years","65 Years",{"count":52,"type":53},60,"ESTIMATED","INTERVENTIONAL",[56],"NA","The clinical performance of a bioactive composite (alkasite-based), a nanohybrid resin composite and a bulk-fill resin composite in class II restorations will be evaluated and compared. After recruiting participants with at least 3 approximal caries lesions, all restorations will be placed by a single clinician. All caries lesions will be removed before restoring. Cavities will be divided into three groups: a bioactive composite \\[Cention Forte Ivoclar Vivadent, Schaan, Liechtenstein\\], a nanohybrid resin composite \\[Tetric N-Ceram2 (Ivoclar Vivadent, Schaan, Liechtenstein)\\] and a bulk-fill resin composite \\[Tetric N-PowerFill2 (Ivoclar Vivadent, Schaan, Liechtenstein)\\], All restorative procedures will be conducted according to manufacturers' instructions. Restorations will be scored using FDI criteria after a week (baseline) 6, 12, 24, 36 and 48 months. Descriptive statistics will be performed using chi-square tests.",[59],"Tooth Disease","NOT_YET_RECRUITING","2026-04-27",{"date":63,"type":64},"2026-05-01","ACTUAL",{"date":66,"type":53},"2026-04-28",{"date":68,"type":53},"2028-06-28",{"name":5,"class":6}]