[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589549":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":11,"locations":20,"responsibleParty":32,"collaborators":11,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":11,"eligibilityCriteria":40,"healthyVolunteers":36,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":11,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":53,"overallStatus":55,"whyStopped":11,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"Institute of Hematology & Blood Diseases Hospital, China","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"The group of rhTPO","EXPERIMENTAL",null,[13],"Drug: Recombinant Human Thrombopoietin（rhTPO）",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DRUG","Recombinant Human Thrombopoietin（rhTPO）","G-CSF will be administered at a dose of 10 μg\u002Fkg\u002Fday subcutaneously for 7-10 days post-chemotherapy.\n\nrhTPO is started on the same day as G-CSF at 300 U\u002Fkg\u002Fd and injected subcutaneously until the stem cell collection was completed.",[9],[21],{"facility":22,"status":11,"city":23,"state":11,"zip":11,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":11},"Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences","Tianjin","China","CN",{"type":27,"coordinates":28},"Point",[29,30],117.17667,39.14222,{"lat":30,"lon":29},{"type":33,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100589549","clinical-study-of-rhtpo-in-hematopoietic-stem-cell-mobilization-for-autologous-transplantation-in-acute-leukemia-100589549",false,"NCT06955858","Clinical Study of rhTPO in Hematopoietic Stem Cell Mobilization for Autologous Transplantation in Acute Leukemia","Recombinant Human Thrombopoietin for Autologous Hematopoietic Stem Cell Mobilization in Acute Leukemia: A Single-Arm Prospective Study","Inclusion Criteria:\n\n1. Age 18～65 years, regardless of gender.\n2. Histopathologically confirmed acute leukemia with immunohistochemical validation\n3. Sustained complete hematologic remission with documented minimal residual disease (MRD) negativity.\n4. Eastern Cooperative Oncology Group (ECOG) performance status smaller than 2 and a life expectancy of more than 6 months\n5. No active infectious disease; no severe organ failure.\n6. Willingness to participate with written informed consent for study enrollment.\n\nExclusion Criteria:\n\n1. Liver dysfunction (alanine aminotransferase or bilirubin greater than two times the normal upper limit).\n2. Renal dysfunction (creatinine or urea higher than 1.5 times the normal upper limit).\n3. Any disease that could put patients at high risk, including but not limited to unstable cardiac disease, uncontrolled atrial fibrillation or hypertension, severe diabetic retinopathy\n4. rhTPO aller- gies.\n5. Severe prior thrombosis-event.\n6. History of other malignancy, unless cured for more than 3 years\n7. Pregnant or lactating women\n8. Severe infectious disease (uncured tuberculosis, pulmonary aspergillosis)\n9. Epilepsia, dementia or any mental disease requiring treatment.\n10. Other conditions deemed inappropriate for study participation by the investigator.","ALL","18 Years","65 Years",{"count":45,"type":46},60,"ESTIMATED","INTERVENTIONAL",[49],"NA","Evaluation of the efficacy and safety of recombinant human thrombopoietin (rhTPO) at 300 U\u002Fkg\u002Fday for hematopoietic stem cell mobilization in autologous transplantation among acute leukemia patients",[52],"Hematopoietic Stem Cell Mobilization",[54],"Recombinant Human Thrombopoietin","NOT_YET_RECRUITING","2025-04-30",{"date":58,"type":59},"2025-05-02","ACTUAL",{"date":61,"type":46},"2025-05-30",{"date":63,"type":46},"2026-12-30",{"name":5,"class":6},1]