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Age 18-75 years old, no gender limitation;\n2. Pathologically confirmed gastric or gastroesophageal junction adenocarcinoma with cTNM stage II\u002FIII，T≥3, N ≥0, M=0；\n3. Expected survival of ≥ 3 months;\n4. The tumor specimens were PD-L1 positive (CPS ≥ 1)；\n5. There is a measurable lesion with the possibility of radical R0 resection after evaluation by doctors；\n6. Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1;\n7. Patients informed about the purpose and course of the study and provided a written consent to participate.\n\nExclusion Criteria:\n\n1. Use of taurine agent within 1 month prior to the first dose of study treatment and throughout the study;\n2. Patients with positive HER-2；\n3. Patients with gastrointestinal obstruction or active bleeding in the gastrointestinal tract, as well as perforation and dysphagia;\n4. Patients with severe heart, lung, liver, kidney, endocrine, hematopoietic system or psychiatric diseases were considered not suitable for the study group;\n5. Human immunodeficiency virus (HIV) infection or known acquired immune deficiency syndrome (AIDS) or autoimmune disease or immunosuppressant use；\n6. 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