[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631108":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":43,"locations":30,"responsibleParty":49,"collaborators":30,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":30,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":30,"enrollmentInfo":59,"targetDuration":30,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":30,"overallStatus":70,"whyStopped":30,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":30},{"fullName":5,"class":6},"Ruijin Hospital","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Ultrasound-Guided Group","EXPERIMENTAL","Subglottic suctioning is performed under ultrasound imaging guidance.",[13],"Other: ultrasound-guided suction",{"label":15,"type":16,"description":17,"interventionNames":18},"Continuous Suctioning Group","ACTIVE_COMPARATOR","Provide continuous subglottic suction for 24 hours.",[19],"Other: Continuous subglottic suction",{"label":21,"type":16,"description":22,"interventionNames":23},"Intermittent Suctioning Group","Intermittent suctioning is performed in accordance with the recommended timing for subglottic suctioning as outlined in 'Operational Guidelines for Subglottic Suctioning under Artificial Airway'.",[24],"Other: Intermittent subglottic suction",[26,31,35],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"ultrasound-guided suction","In accordance with the recommended timing for subglottic suctioning as outlined in 'Operational Guidelines for Subglottic Suctioning under Artificial Airway', subglottic suctioning is performed under ultrasound imaging guidance. Based on semi-quantitative assessment of secretions via ultrasound airway examination, suctioning is administered if the score is ≥1. After suctioning is completed, ultrasound re-evaluation is conducted, and the procedure continues until the score equals 0, at which point the operation concludes.",[9],null,{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Continuous subglottic suction","Provide continuous subglottic suction for 24 hours by connecting to a central negative pressure device, using constant negative pressure for continuous suction. The suction pressure is maintained at: 40\\~60 mmHg.",[15],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Intermittent subglottic suction","Suction time is the same as that of the ultrasound-guided group. The device uses a bedside wall-mounted negative pressure suction apparatus, with the suction pressure maintained at 100 \\~ 150 mmHg (1 mmHg = 0.133 Kpa). The operation is ended based on the operator's experience.",[21],[40],{"name":41,"affiliation":5,"role":42},"weiqing Zhang, Ph.D.","PRINCIPAL_INVESTIGATOR",[44],{"name":45,"role":46,"phone":47,"phoneExt":30,"email":48},"weiqing zhang, Ph.D.","CONTACT","86 18521525300","weiq.zh@163.com",{"type":50,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100631108","clinical-study-on-the-efficacy-of-subglottic-suction-in-mechanically-ventilated-patients-guided-by-bedside-ultrasound-100631108",false,"NCT07496385","Clinical Study on the Efficacy of Subglottic Suction in Mechanically Ventilated Patients Guided by Bedside Ultrasound","Inclusion Criteria:\n\n* 1\\. Patients admitted to the ICU with the patient or their legal representative having signed an informed consent form; 2. Patients expected to have an oral artificial airway in place for ≥72 hours; 3. Patients using tracheostomy tubes with subglottic suctioning\n\nExclusion Criteria:\n\n* 1\\) Severe cervical deformity, extensive subcutaneous emphysema, thick dressing coverage, or severe obesity that prevents clear visualization of the subglottic region by ultrasound.\n\n  2\\) Coagulopathy (platelets \\\u003C50×10⁹\u002FL) or active bleeding tendency, which may induce airway bleeding due to suctioning procedures.\n\n  3\\) Presence of organic airway disease or previous cervical surgery history, affecting assessment of the subglottic region.\n\n  4\\) Tracheostomy patients. 5) Patients allergic to ultrasound coupling agents, or those unable to cooperate with cervical ultrasound examination due to severe agitation.\n\n  6\\) Patients with existing pulmonary infection upon admission. 7) Patients intubated for treatment of known aspiration. 8) History of lung cancer or head and neck cancer that may produce alpha-amylase in the lungs.\n\n  9\\) History of conditions affecting salivary secretion (e.g., Sjögren's syndrome).","ALL","18 Years",{"count":60,"type":61},321,"ESTIMATED","INTERVENTIONAL",[64],"NA","Subglottic suctioning, as an important airway management technique, has its operational accuracy and safety directly impacting patient prognosis. Therefore, improving the effectiveness and safety of subglottic suctioning has become a focus of clinical attention. Point-of-care ultrasound, which can provide imaging, can be used to guide subglottic suctioning, enhancing the intuitiveness of the procedure. This study aims to evaluate the safety and effectiveness of subglottic suctioning guided by point-of-care ultrasound in mechanically ventilated patients, in order to help standardize clinical practice and improve medical quality.",[67,68,69],"Ultrasound Guidance","Subglottic Airway Injury","Airway Management","NOT_YET_RECRUITING","2026-03-22",{"date":73,"type":74},"2026-03-27","ACTUAL",{"date":76,"type":61},"2026-04-01",{"date":78,"type":61},"2027-08-01",{"name":5,"class":6}]