[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623536":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":49,"locations":56,"responsibleParty":70,"collaborators":36,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":75,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":36,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":98,"whyStopped":36,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Universidad Católica San Antonio de Murcia","OTHER",[8,15,21,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","PLACEBO_COMPARATOR","Subjects in this group will consume a placebo product (maltodextrin) with the same organoleptic characteristics as the investigational product.",[13,14],"Dietary Supplement: Control placebo","Other: No Physical Exercise",{"label":16,"type":17,"description":18,"interventionNames":19},"Natural extract","EXPERIMENTAL","Subjects in this group will consume the investigational product (experimental product composed of a combination of six natural extracts: grapefruit extract, apigenin, orange extract, luteolin, yerba mate extract, and olive leaf extract).",[20,14],"Dietary Supplement: Experimental Product",{"label":22,"type":17,"description":23,"interventionNames":24},"Physical exercise and consumption of experimental product","During the study, subjects must consume the experimental product and also follow a training program. A multi-component program will be carried out during the 4 months of product consumption. Sessions will last 60 minutes and will be held 2-3 times per week.",[20,25],"Other: Physical exercise",{"label":27,"type":10,"description":28,"interventionNames":29},"Physical exercise and consumption of placebo product","During the study, subjects must consume the placebo product and also follow a training program. A multi-component program will be carried out during the 4 months of product consumption. Sessions will last 60 minutes and will be held 2-3 times per week.",[13,25],[31,37,41,45],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DIETARY_SUPPLEMENT","Experimental Product","Supplement consisting of orange extract, apigenin, luteolin, yerba mate extract, grapefruit extract, and olive leaf extract.",[16,22],null,{"type":32,"name":38,"description":39,"armGroupLabels":40,"otherNames":36},"Control placebo","Product with identical characteristics to the experimental product.",[27,9],{"type":6,"name":42,"description":43,"armGroupLabels":44,"otherNames":36},"Physical exercise","During the study, subjects will have to develop a training program. A multicomponent program will be carried out during the 4 months of product consumption. The sessions will last 60 minutes and will be held 2-3 times per week.",[22,27],{"type":6,"name":46,"description":47,"armGroupLabels":48,"otherNames":36},"No Physical Exercise","During the study, subjects will only consume the product assigned to them in the randomization.",[16,9],[50],{"name":51,"role":52,"phone":53,"phoneExt":54,"email":55},"Francisco Javier López Román","CONTACT","968278157","157","jlroman@ucam.edu",[57],{"facility":58,"status":36,"city":59,"state":36,"zip":36,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"UCAM HiTech, Sport & Health Innovation Hub","Murcia","Spain","ES",{"type":63,"coordinates":64},"Point",[65,66],-1.13004,37.98704,{"lat":66,"lon":65},[69],{"name":51,"role":52,"phone":53,"phoneExt":54,"email":55},{"type":71,"investigatorFullName":51,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Bachelor of Medicine","100623536","clinical-trial-on-a-natural-compound-to-improve-chronic-inflammation-after-sars-cov-2-infection-100623536",false,"NCT07397910","Clinical Trial on a Natural Compound to Improve Chronic Inflammation After SARS-CoV-2 Infection","Clinical Trial to Analyze the Effectiveness of a Natural Compound on Chronic Immune-mediated Inflammatory Status in Subjects Who Have Had SARS-CoV-2 Infection.","NUTRACOVID","Inclusion Criteria:\n\n* Subjects of both sexes.\n* Subjects over 18 and under 70 years of age who have had a SARS-CoV-2 infection diagnosed by PDIA.\n* Subjects with a history of SARS-CoV-2 infection who, three months after the onset of COVID-19, continue to experience symptoms lasting at least two months that cannot be explained by another cause. These symptoms may be newly developed after initial recovery from an acute COVID-19 episode or persist from the initial illness.\n* No history of sequelae from a severe acute illness.\n\nExclusion Criteria:\n\n* Subjects with an underlying disease that explains the clinical manifestations.\n* Presence of chronic inflammatory diseases.\n* Subjects with acute infections.\n* Evidence of active thromboembolic disorder, defined as those receiving parenteral anticoagulant or thrombolytic treatment.\n* Excessive alcohol consumption.\n* Hypersensitivity or intolerance to any of the components of the study products.\n* Use of any nutraceutical or dietary supplement.\n* Severe or terminal illnesses.\n* Subjects with a body mass index (BMI) over 32.\n* Pregnant or lactating women.","ALL","18 Years","70 Years",{"count":85,"type":86},40,"ESTIMATED","INTERVENTIONAL",[89],"NA","A controlled, randomized clinical trial is proposed to demonstrate the effectiveness of the experimental product in controlling hepato-pulmonary inflammation and neurovascular encephalic inflammation, which may constitute the etiopathogenic basis of persistent COVID. In addition, an individualized training program will be implemented for each participant in order to improve chronic symptoms and, consequently, their quality of life.",[92],"Long COVID",[94,95,96,97],"LongCOVID","Nutraceutical","Immune-inflammatory state","Exercise","NOT_YET_RECRUITING","2026-02-02",{"date":101,"type":102},"2026-02-09","ACTUAL",{"date":104,"type":86},"2026-02-23",{"date":106,"type":86},"2026-08-03",{"name":5,"class":6},1]