[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100220642":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":18,"locations":27,"responsibleParty":53,"collaborators":55,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":7,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":7,"enrollmentInfo":7,"targetDuration":7,"studyType":68,"phases":7,"briefSummary":69,"conditions":70,"keywords":75,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Seoul National University Hospital","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"BIOLOGICAL","cultivated oral mucosal epithelial sheet transplantation","Autologous cultivated oral mucosal epithelial cell sheet transplantation using oral mucosal adult stem cells in the patients with intractable corneal limbal deficiency",[14],{"name":15,"affiliation":16,"role":17},"Mee Kum Kim, MD, PhD","Department of Ophthalmology, Seoul National University College of Medicine","PRINCIPAL_INVESTIGATOR",[19,23],{"name":15,"role":20,"phone":21,"phoneExt":7,"email":22},"CONTACT","82-10-6277-0798","kmk9@snu.ac.kr",{"name":24,"role":20,"phone":25,"phoneExt":7,"email":26},"Yu Jeong Kim, MD","82-10-2559-1377","21cnasa@naver.com",[28,46],{"facility":5,"status":29,"city":30,"state":30,"zip":31,"country":32,"countryCode":7,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"AVAILABLE","Seoul","110-744","South Korea",{"type":34,"coordinates":35},"Point",[36,37],126.9784,37.566,{"lat":37,"lon":36},[40,41,45],{"name":15,"role":20,"phone":21,"phoneExt":7,"email":22},{"name":42,"role":20,"phone":43,"phoneExt":7,"email":44},"Dong Hyun Kim, MD","82-10-3737-0975","amidfree@gmail.com",{"name":15,"role":17,"phone":7,"phoneExt":7,"email":7},{"facility":47,"status":29,"city":30,"state":30,"zip":31,"country":32,"countryCode":7,"cosmosGeoPoint":48,"geoPoint":50,"contacts":51},"Seoul National Unversity Hospital",{"type":34,"coordinates":49},[36,37],{"lat":37,"lon":36},[52],{"name":15,"role":20,"phone":21,"phoneExt":7,"email":22},{"type":54,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[56],{"name":57,"class":58},"Ministry of Health & Welfare, Korea","OTHER_GOV","100220642","clinical-trial-on-the-effect-of-autologous-oral-mucosal-epithelial-sheet-transplantation-100220642",false,"NCT02149732","Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation","An Investigator-initiated Trial (IIT) on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation in Corneal Limbal Deficiency Patients","Inclusion Criteria:\n\n1. patient with eye which has limbal stem cell deficiency and conjunctivalization of cornea\n2. patient who shows no improvement after limbal tissue or amniotic membrane transplantation, or who has difficulty in receiving long-term immunosuppressive treatment\n3. patient who agree this clinical trial\n4. patient with the eyes in which best corrected visual acuity is less than counting finger\n5. patient who is older than sixteen year old\n\nExclusion Criteria:\n\n1. patient who has relevant corneal transparency\n2. patient who is on the pregnancy or has a plan of pregnancy within 1 year\n3. patient who has corneal infection\n4. patient who has diagnosis of HBV, HCV, HIV, syphilis\n5. patinet who has past medial history of antinal, myocardial infarction, heart failure, arrhythmia, brain stroke, cerebrovascular disease\n6. patient who has malignancy\n7. patient who shows hypersensitivity to bovine protein.","ALL","16 Years","EXPANDED_ACCESS","To investigate the effect of ocular surface reconstruction and assess the safety in cultivated oral mucosal epithelial cell sheet transplantation (COMET) regarding patients with cicatricial change of ocular surface.",[71,72,73,74],"Limbal Stem Cell Deficiency","Stevens-johnson Syndrome","Ocular Cicatricial Pemphigoid","Chemical Burn",[76,77,78],"Limbal stem cell deficiency","Cultivated oral mucosal cell sheet transplantation","Ocular surface reconstruction","2016-04-18",{"date":81,"type":82},"2016-04-20","ESTIMATED",{"date":84,"type":7},"2014-05",{"date":86,"type":82},"2016-12",{"name":5,"class":6},2]