[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548465":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":59,"collaborators":24,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":24,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":24,"enrollmentInfo":71,"targetDuration":24,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":24,"overallStatus":43,"whyStopped":24,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Scripps Health","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute and Subacute Phases of CRPS","EXPERIMENTAL","Participants diagnosed with acute and subacute phases of CRPS will be assigned to this group.",[13],"Device: Spinal Cord Stimulation Device",{"label":15,"type":10,"description":16,"interventionNames":17},"Chronic Phase of CRPS","Participants diagnosed with chronic CRPS will be assigned to this group.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Spinal Cord Stimulation Device","The closed-loop spinal cord stimulation mechanism uses dynamic adjusting stimulation parameters based on real-time physiologic response and is uniquely positioned to mitigate the aberrant inflammatory and neurosensory processing and autonomic dysfunction driving CRPS and its progression between phases.",[9,15],null,[26],{"name":27,"affiliation":28,"role":29},"David B Hiller, MD","Physician","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},"Julie C McCauley","CONTACT","585-554-7122","mccauley.julie@scrippshealth.org",{"name":37,"role":33,"phone":38,"phoneExt":24,"email":39},"Roslyn M Kackman","858-554-7122","kackman.roslyn@scrippshealth.org",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Scripps Clinic Torrey Pines","RECRUITING","La Jolla","California","92037","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-117.2742,32.84727,{"lat":53,"lon":52},[56,57,58],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},{"name":37,"role":33,"phone":38,"phoneExt":24,"email":39},{"name":27,"role":29,"phone":24,"phoneExt":24,"email":24},{"type":29,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"David Hiller, MD","Principal Investigator","100548465","closed-loop-spinal-cord-stimulation-for-complex-regional-pain-syndrome-100548465",false,"NCT06421350","Closed Loop Spinal Cord Stimulation for Complex Regional Pain Syndrome","Efficacy of Closed-Loop Spinal Cord Stimulation for Complex Regional Pain Syndrome","Inclusion Criteria:\n\n* 18 years or older\n* neuromodulation naive patients with unilateral CRPS type 1 or type 2 (defined by Budapest Criteria)\n* pre-procedure psychological clearance\n\nExclusion Criteria:\n\n* younger than 18 years\n* prior neuromodulation including spinal cord stimulation\n* prior dorsal root ganglion stimulation\n* prior peripheral nervous system stimulation\n* anatomical obstacles to dorsal column lead placement","ALL","18 Years",{"count":72,"type":73},32,"ESTIMATED","INTERVENTIONAL",[76],"NA","The primary purpose of this study is to determine the differences in response to treatment of complex regional pain syndrome with a closed-loop spinal cord stimulator if applied in the early phases (acute or subacute) versus the chronic phase.",[79],"Complex Regional Pain Syndromes","2025-10-30",{"date":82,"type":83},"2025-11-03","ACTUAL",{"date":85,"type":83},"2024-09-03",{"date":87,"type":73},"2026-06",{"name":5,"class":6},1]