[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618792":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":38,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":10,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":10,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":10,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"Chinese Academy of Medical Sciences, Fuwai Hospital","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Cardiac Implantable Electronic Device Cohort",null,[12],"Other: Cardiac Magnetic Resonance Imaging",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"Cardiac Magnetic Resonance Imaging","Cardiac magnetic resonance imaging performed as part of routine clinical care. Imaging data are used for observational research analyses only, without altering clinical management.",[9],[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Xinqiao Lian","CONTACT","18810639895","lxq010126@163.com",[25],{"facility":10,"status":26,"city":27,"state":10,"zip":10,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"RECRUITING","Beijing","China","CN",{"type":31,"coordinates":32},"Point",[33,34],116.39723,39.9075,{"lat":34,"lon":33},[37],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Minjie Lu","Principal Investigator","100618792","cmr-based-prognostic-study-in-patients-with-cardiac-implantable-electronic-devices-100618792",false,"NCT07336225","CMR-Based Prognostic Study in Patients With Cardiac Implantable Electronic Devices","Prognostic Value of Cardiovascular Magnetic Resonance in Patients With Cardiac Implantable Electronic Devices","Inclusion Criteria:\n\n1. Adult patients (≥18 years old).\n2. Patients with guideline-based indications for cardiac implantable electronic device (CIED) therapy, including pacemaker, implantable cardioverter-defibrillator, or cardiac resynchronization therapy.\n3. Patients who underwent cardiovascular magnetic resonance (CMR) imaging as part of routine clinical evaluation prior to CIED implantation or consideration of CIED therapy.\n\nExclusion Criteria:\n\n1. Patients younger than 18 years of age.\n2. Patients with non-diagnostic or poor-quality CMR images that preclude reliable image analysis.\n3. Patients with incomplete key clinical data or missing follow-up information for primary outcome assessment.\n4. Patients with prior heart transplantation or implantation of ventricular assist devices before CMR examination.\n5. Patients with congenital heart disease requiring surgical correction.","ALL","18 Years",{"count":52,"type":53},1500,"ESTIMATED","OBSERVATIONAL","Cardiac implantable electronic devices (CIEDs) are widely used to treat patients with heart failure, malignant arrhythmias, and other conditions. However, accurately identifying suitable candidates for CIED implantation remains a clinical challenge. Cardiovascular magnetic resonance imaging (CMR) provides a comprehensive assessment of cardiac structure, function, and tissue characteristics, facilitating evaluation of the myocardial substrate for arrhythmias. This study aims to evaluate the prognostic value of multiparametric CMR-derived imaging markers in CIED patients through preoperative CMR examinations. Imaging parameters of interest include structural-functional indices, myocardial strain, late gadolinium enhancement, entropy, and T1 and T2 mapping. Long-term clinical outcomes will be obtained from existing medical records and follow-up. The primary endpoint is sudden cardiac death (SCD) or SCD-equivalent events, defined as SCD, resuscitated cardiac arrest, sustained ventricular tachycardia or ventricular fibrillation, or appropriate ICD therapy. Secondary endpoints include all-cause mortality or heart failure rehospitalization. This study aims to elucidate the role of CMR in assessing CIED treatment indications and long-term risk stratification, thereby helping to optimize CIED implantation decisions.",[57],"Arrhythmias","2026-01-25",{"date":60,"type":61},"2026-01-27","ACTUAL",{"date":63,"type":61},"2010-01-01",{"date":65,"type":53},"2040-12-31",{"name":5,"class":6},1]