[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645278":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":31,"centralContacts":35,"locations":45,"responsibleParty":66,"collaborators":22,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":22,"enrollmentInfo":78,"targetDuration":22,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":47,"whyStopped":22,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"The Cleveland Clinic","OTHER",[8,14,18,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1: - loss of smell + CRS with nasal polyps (CRSwNP)","ACTIVE_COMPARATOR","Loss of smell + CRS with nasal polyps (CRSwNP)",[13],"Other: Smell Training",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2: - loss of smell with no CRS\u002Fno polyps - undergo 3 months of smell training","Loss of smell + CRS with nasal polyps (CRSwNP) - undergo 3 months of smell training",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Control Group 1: - no loss of smell CRS with nasal polyps (CRSwNP)","NO_INTERVENTION","No loss of smell CRS with nasal polyps (CRSwNP)",null,{"label":24,"type":20,"description":25,"interventionNames":22},"Control Group 2: -no loss of smell \u002F no CRS\u002Fno polyps","No loss of smell \u002F no CRS\u002Fno polyps",[27],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":22},"Smell Training","Patients experiencing loss of smell from chronic rhinosinusitis (CRS)will undergo smell training.",[9,15],[32],{"name":33,"affiliation":5,"role":34},"Mohamad Chaaban, MD","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":22,"email":40},"John O'Neill","CONTACT","4405062611","ONEILLJ2@ccf.org",{"name":42,"role":38,"phone":43,"phoneExt":22,"email":44},"Christopher Novicky","216-444-7018","novickc@ccf.org",[46],{"facility":5,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Cleveland","Ohio","44195","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-81.69541,41.4995,{"lat":57,"lon":56},[60,61,64],{"name":37,"role":38,"phone":39,"phoneExt":22,"email":40},{"name":62,"role":38,"phone":43,"phoneExt":22,"email":63},"Hana Rosen","rosenh@ccf.org",{"name":65,"role":34,"phone":22,"phoneExt":22,"email":22},"Mohamad Chaaban",{"type":67,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100645278","cognitive-and-immunologic-profiles-of-patients-with-olfactory-dysfunction-after-smell-training-100645278",false,"NCT07681973","Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training","CIPOD","Inclusion Criteria:\n\n* Age less than 18 years-old\n* Present to rhinology clinic with CRS with nasal polyps\n* Sense of smell loss for any reason (other than trauma or tumor)\n\nExclusion Criteria:\n\n* Patients \\\u003C 18 years of age\n* Individuals with unilateral nasal polyps\n* Autoimmune diseases\n* Ciliary disorders\n* Cystic fibrosis\n* Smell loss due to tumors or trauma",true,"ALL","18 Years",{"count":79,"type":80},52,"ESTIMATED","INTERVENTIONAL",[83],"NA","A research study to assess the baseline olfactory function, mental health status, clinical severity, and immunological profile in patients with smell loss. The impact of a 3-month olfactory training program on smell function, immunological changes, and mental health in patients with smell loss will be evaluated.\n\nThe primary purpose of this study is to investigate tissue and blood samples to identify molecules that may be related to smell loss, ultimately aiming to develop future treatments for this condition and correlate with cognition.",[86,87],"Smell Loss","Chronic Rhinosinusitis (CRS)",[86,89,90,91],"Chronic Rhinosinusitis","Nasal Polyps","CRSwNP","2026-06-26",{"date":94,"type":95},"2026-07-02","ACTUAL",{"date":97,"type":95},"2025-12-09",{"date":99,"type":80},"2027-03-31",{"name":5,"class":6},1]