[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617430":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":33,"locations":39,"responsibleParty":71,"collaborators":73,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":79,"sex":85,"minAge":86,"maxAge":26,"enrollmentInfo":87,"targetDuration":26,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":98,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Medstar Health Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Virtual reality delivered behavioral skills for pain management","EXPERIMENTAL","Participants use VR-CAN therapy at home, 10 minutes per session, daily for 14 days",[13],"Device: VR-CAN prototype chronic cancer pain therapy -- virtual reality program delivering CBT for chronic cancer pain management",{"label":15,"type":16,"description":17,"interventionNames":18},"Tablet-based delivery of behavioral skills for pain management","ACTIVE_COMPARATOR","Participants use a two-dimensional skills-based intervention delivered by handheld tablet at home, 10 minutes per session, daily for 14 days",[19],"Device: Active Control -- two-dimensional tablet-delivered intervention",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","VR-CAN prototype chronic cancer pain therapy -- virtual reality program delivering CBT for chronic cancer pain management","VR-CAN participants will be instructed to use the prototype VR-CAN software on the VR device at home daily for two weeks, at least 10 minutes per session, beginning the day after enrollment.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Active Control -- two-dimensional tablet-delivered intervention","Tablet-based active control participants will follow the same prescription as the experimental arm (i.e., using assigned technology \\>10 min\u002Fdaily for two weeks at home), except they will view a two-dimensional, non-CBT skills version using a tablet device.",[15],[32],"Handheld tablet delivered two-dimensional skills based intervention",[34],{"name":35,"role":36,"phone":37,"phoneExt":26,"email":38},"Hunter Groninger, MD","CONTACT","202-877-7445","hunter.groninger@medstar.net",[40,56],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"MedStar Health Research Institute","RECRUITING","Washington D.C.","District of Columbia","20010","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-77.03637,38.89511,{"lat":52,"lon":51},[55],{"name":35,"role":36,"phone":37,"phoneExt":26,"email":38},{"facility":57,"status":42,"city":58,"state":59,"zip":60,"country":46,"countryCode":47,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Duke University School of Medicine","Durham","North Carolina","27710",{"type":49,"coordinates":62},[63,64],-78.89862,35.99403,{"lat":64,"lon":63},[67],{"name":68,"role":36,"phone":69,"phoneExt":26,"email":70},"Sarah Kelleher, PhD","919-416-3405","sarah.kelleher@duke.edu",{"type":72,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[74],{"name":75,"class":76},"National Cancer Institute (NCI)","NIH","100617430","cognitive-behavioral-theory-assisted-virtual-reality-for-chronic-cancer-pain-vr-can-100617430",false,"NCT07318519","Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)","Cognitive Behavioral Theory-assisted Virtual Reality for Chronic Cancer Pain (VR-CAN): Device Prototype Development and Feasibility Testing","VR-CAN","Inclusion Criteria:\n\n* age at least 18 years old\n* cancer diagnosis, undergoing treatment\n* chronic cancer pain (i.e., cancer pain at least 3 months duration) with baseline pain severity at least 4\u002F10 (where 0=no pain, 10=worst pain)\n\nExclusion Criteria:\n\n* intractable nausea\u002Fvomiting, motion sickness, seizures\u002Fepilepsy, and\u002For cranial structures\u002Fabnormalities preventing VR headset use\n* moderate-severe pain of non-cancer etiology\n* enrolled in another pain study\n* unable to complete survey measures or interviews in English or Spanish","ALL","18 Years",{"count":88,"type":89},40,"ESTIMATED","INTERVENTIONAL",[92],"NA","While chronic cancer pain affecting as many as 75% of patients is typically addressed using pharmacologic interventions, experts and patients alike support maximizing any relevant non-pharmacologic interventions as well, such as cognitive behavioral therapy. Virtual reality, a novel technology that can temporarily immerse users in a calm, pleasant environment, has been increasingly shown to facilitate improvement in different acute and chronic pain syndromes by providing distraction from pain and lowering pain sensation. To address the significant needs of patients living with chronic cancer pain, we aim to develop and pilot test a prototype device that will leverage cognitive behavioral therapy principles to deliver a novel virtual reality pain therapy. The investigators will do this through the following steps:\n\nStep 1. Develop and refine a CBT-assisted VR prototype for patients with chronic cancer pain (VR-CAN).\n\nStep 2. Conduct a randomized controlled trial to examine the feasibility, acceptability, usability, safety, and initial clinical impact of the developed VR-CAN prototype compared to a tablet-based two-dimensional video control group.\n\nStep 3. Collect and evaluate qualitative post-intervention data on VR-CAN participants' preferences, thoughts, and feelings about the VR-CAN technology and protocol to optimize for a future, larger, fully powered randomized controlled trial.",[95,96,97],"Cancer","Cancer Pain","Chronic Cancer Pain",[99,100,101,102,103],"cancer","pain","chronic pain","cognitive behavioral therapy","virtual reality","2026-01-02",{"date":106,"type":107},"2026-01-06","ACTUAL",{"date":109,"type":107},"2025-07-01",{"date":111,"type":89},"2027-05-31",{"name":5,"class":6},2]