[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100480983":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":50,"centralContacts":51,"locations":61,"responsibleParty":93,"collaborators":95,"id":101,"slug":102,"hasResults":103,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":108,"sex":109,"minAge":110,"maxAge":111,"enrollmentInfo":112,"targetDuration":50,"studyType":115,"phases":116,"briefSummary":118,"conditions":119,"keywords":128,"overallStatus":64,"whyStopped":50,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":140},{"fullName":5,"class":6},"Colorado State University","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Cognitive-Behavioral Therapy followed by Exercise Training","EXPERIMENTAL","6-week cognitive-behavioral therapy intervention of 6 weekly 1-hour group sessions followed by a 6-week exercise training intervention of 6 weekly 1-hour group sessions",[13],"Behavioral: Cognitive-Behavioral Therapy followed by Exercise Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Exercise Training followed by Cognitive-Behavioral Therapy","ACTIVE_COMPARATOR","6-week exercise training intervention of 6 weekly 1-hour group sessions followed by a 6-week cognitive-behavioral therapy intervention of 6 weekly 1-hour group sessions",[19],"Behavioral: Exercise Training followed by Cognitive-Behavioral Therapy",{"label":21,"type":16,"description":22,"interventionNames":23},"Exercise Training Only","6-week exercise training intervention of 6 weekly 1-hour group sessions followed by an additional 6-week exercise training intervention of 6 weekly 1-hour group sessions",[24],"Behavioral: Cognitive-Behavioral Therapy Only",{"label":26,"type":16,"description":27,"interventionNames":28},"Cognitive-Behavioral Therapy Only","6-week cognitive-behavioral therapy intervention of 6 weekly 1-hour group sessions followed by an additional 6-week cognitive-behavioral therapy intervention of 6 weekly 1-hour group sessions",[29],"Behavioral: Exercise Training Only",[31,37,42,47],{"type":32,"name":9,"description":33,"armGroupLabels":34,"otherNames":35},"BEHAVIORAL","6-week group CBT (cognitive-behavioral therapy; 1 hour\u002Fweek for 6 weeks) followed by 6-week group exercise training (1 hour\u002Fweek for 6 weeks). Home practice is assigned throughout the 12-week intervention period.",[9],[36],"CBT->Exercise Training",{"type":32,"name":15,"description":38,"armGroupLabels":39,"otherNames":40},"6-week group exercise training (1 hour\u002Fweek for 6 weeks) followed by 6-week group CBT (1 hour\u002Fweek for 6 weeks). Home practice is assigned throughout the 12-week intervention period.",[15],[41],"Exercise Training -> CBT",{"type":32,"name":26,"description":43,"armGroupLabels":44,"otherNames":45},"6-week group CBT (1 hour\u002Fweek for 6 weeks), with continuation of group CBT for a second 6-week period (1 hour\u002Fweek for 6 weeks). Home practice is assigned throughout the 12-week intervention period.",[21],[46],"CBT Only",{"type":32,"name":21,"description":48,"armGroupLabels":49,"otherNames":50},"6-week group exercise training (1 hour\u002Fweek for 6 weeks), with continuation of group exercise for a second 6-week period (1 hour\u002Fweek for 6 weeks). Home practice is assigned throughout the 12-week intervention period.",[26],null,[52,57],{"name":53,"role":54,"phone":55,"phoneExt":50,"email":56},"Lauren B Shomaker, PhD","CONTACT","970-491-3217","lauren.shomaker@colostate.edu",{"name":58,"role":54,"phone":59,"phoneExt":50,"email":60},"Madison Bristol","720-777-6128","madison.bristol@childrenscolorado.org",[62,80],{"facility":63,"status":64,"city":65,"state":66,"zip":67,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":75,"contacts":76},"Children's Hospital Colorado","RECRUITING","Aurora","Colorado","80011","United States","US",{"type":71,"coordinates":72},"Point",[73,74],-104.83192,39.72943,{"lat":74,"lon":73},[77],{"name":78,"role":54,"phone":79,"phoneExt":50,"email":60},"Madison Bristol, MPH","720-777-6607",{"facility":5,"status":64,"city":81,"state":66,"zip":82,"country":68,"countryCode":69,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"Fort Collins","80523",{"type":71,"coordinates":84},[85,86],-105.08442,40.58526,{"lat":86,"lon":85},[89],{"name":90,"role":54,"phone":91,"phoneExt":50,"email":92},"Natalia Sanchez, MPH","970-491-1120","natalia.sanchez@colostate.edu",{"type":94,"investigatorFullName":50,"investigatorTitle":50,"investigatorAffiliation":50,"oldNameTitle":50,"oldOrganization":50},"SPONSOR",[96,99],{"name":97,"class":98},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH",{"name":100,"class":6},"University of Colorado, Denver","100480983","cognitive-behavioral-therapy-and-exercise-training-in-adolescents-at-risk-for-type-2-diabetes-100480983",false,"NCT05543083","Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes","CBTeX","Inclusion Criteria:\n\n* Female\n* Age 12-17 years\n* Body Mass Index (BMI)\\>= 85 for age and sex\n* Type 2 Diabetes (T2D) first-or second-degree relative\n* Center for Epidemiologic Studies Depression Scale (CES-D) total score \\>=21\n\nExclusion Criteria:\n\n* T2D\u002F Type 1 Diabetes (T1D) or any major medical condition (e.g. cardiovascular, renal) that would prohibit the ability to participate in exercise training\n* Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) conduct disorder, substance abuse\u002F dependence, obsessive compulsive disorder, panic attacks, post-traumatic stress disorder, anorexia\u002Fbulimia, \\& schizophrenia\n* Insulin sensitizers, weight loss medications \\& chronic steroids\n* Structured weight loss treatment or bariatric surgery\n* Pregnancy, nursing",true,"FEMALE","12 Years","17 Years",{"count":113,"type":114},300,"ESTIMATED","INTERVENTIONAL",[117],"NA","The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training groups, decreases stress, improves mood, increases physical activity and physical fitness, and decreases insulin resistance among teenagers at risk for diabetes.",[120,121,122,123,124,125,126,127],"Insulin Resistance","Depression","Depressive Disorder","Mood Disorders","Mental Disorder in Adolescence","Hyperinsulinism","Glucose Metabolism Disorders","Metabolic Disease",[129,130],"Adolescent Type 2 Diabetes Prevention","Exercise Training","2026-04-17",{"date":133,"type":134},"2026-04-22","ACTUAL",{"date":136,"type":134},"2023-06-02",{"date":138,"type":114},"2029-03-31",{"name":5,"class":6},2]