[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597565":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":37,"responsibleParty":52,"collaborators":23,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":23,"eligibilityCriteria":59,"healthyVolunteers":56,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":23,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":40,"whyStopped":23,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"University of Texas at Austin","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Regular CPT","EXPERIMENTAL","Standard-model Cognitive Processing Therapy (CPT) - one 60-min session per week for 12 weeks total",[13],"Behavioral: Regular CPT",{"label":15,"type":10,"description":16,"interventionNames":17},"mCPT","Massed CPT - two 60-min sessions each day for 5 consecutive days (10 sessions total)",[18],"Behavioral: Massed CPT",[20,24],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL",[9],null,{"type":21,"name":25,"description":16,"armGroupLabels":26,"otherNames":23},"Massed CPT",[15],[28],{"name":29,"affiliation":5,"role":30},"Erin Richardson","PRINCIPAL_INVESTIGATOR",[32],{"name":33,"role":34,"phone":35,"phoneExt":23,"email":36},"Research Associate I","CONTACT","512-766-6209","ambreen.rana@austin.utexas.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":23},"University of Texas at Austin, Dell Medical School, Department of Psychiatry","RECRUITING","Austin","Texas","78701","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-97.74306,30.26715,{"lat":50,"lon":49},{"type":30,"investigatorFullName":29,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Advanced Practice Nurse","100597565","cognitive-processing-therapy-cpt-for-perinatal-posttraumatic-stress-disorder-ptsd-100597565",false,"NCT07060144","Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)","Inclusion Criteria:\n\n* Female, ages 18-46, Pregnant (\\\u003C 25 weeks), able to read and write in English, History of at least 1 criterion A trauma, Primary diagnosis of PTSD (confirmed by SCID), Psychotropic medications must be stable with no changes ≥ 2 weeks (≥ 6 weeks for fluoxetine), and no medication changes can be made during the course of therapy\n\nExclusion Criteria:\n\n* Not currently pregnant, Diagnosis of bipolar disorder, psychotic disorders, Suicidal ideation with plan or intent, Substance use disorder, Regular benzodiazepine use (\\> 4x weekly)","FEMALE","18 Years","46 Years",{"count":64,"type":65},60,"ESTIMATED","INTERVENTIONAL",[68],"NA","Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score \\> 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once\u002Fweek for 12 weeks) or massed CPT (mCPT) (an intensive schedule of 12 60-min sessions over 5 days, approximately 2-3 sessions per day) via telemedicine, for treatment of PTSD. The research aims will be three-fold: (1) Evaluate the relative efficacy and tolerability of CPT vs. mCPT for treatment of perinatal PTSD and depression; (2) Determine the effect of CPT upon maternal-infant attachment and interaction; (3) Collect pilot data of obstetric and neonatal outcomes among those receiving the two CPT delivery schedules.",[71,72],"Posttraumatic Stress Disorder (PTSD)","Pregnancy",[74,75,76,77,78],"PTSD","pregnancy","cognitive processing therapy","psychotherapy","trauma","2026-06-15",{"date":81,"type":82},"2026-06-16","ACTUAL",{"date":84,"type":82},"2025-08-01",{"date":86,"type":65},"2027-10",{"name":5,"class":6},1]