[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590220":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Universita di Verona","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Telerehabilitation","EXPERIMENTAL","Three hours of cognitive rehabilitation per week, carried out independently and remotely using a computerized device, which is pre-programmed according to the patient's specific needs.",[13],"Behavioral: Cognitive treatment delivered via telerehabilitation.",{"label":15,"type":16,"description":17,"interventionNames":18},"In-person treatment","ACTIVE_COMPARATOR","Three hours of in-person cognitive rehabilitation per week using a computerized device. The participant will perform cognitive exercises on the computerized device in the presence of the therapist, who will activate the device (using credentials specifically created for them) and select the appropriate activity to administer at each session.",[19],"Behavioral: In-person cognitive treatment.",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Cognitive treatment delivered via telerehabilitation.",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"In-person cognitive treatment.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Valentina Varalta, Doctor","CONTACT","045 8124956","valentina.varalta@univr.it",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Azienda Ospedaliera Universitaria Integrata Verona - UOC di Neuroriabilitazione","RECRUITING","Verona","verona","37134","Italy","IT",{"type":45,"coordinates":46},"Point",[47,48],10.9938,45.43854,{"lat":48,"lon":47},[51],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Valentina Varalta","Doctor","100590220","cognitive-rehabilitation-of-deficits-in-patients-with-multiple-sclerosis-100590220",false,"NCT06964581","Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis","Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis: Proposal for an Integrated Cognitive Treatment in a Telematic Format","Inclusion Criteria:\n\n* Diagnosis of relapsing-remitting multiple sclerosis (RRMS), or primary progressive (PPMS) or secondary progressive (SPMS), defined by at least 3-6 months.\n* Age between 18 and 65 years.\n* Expanded Disability Status Scale (EDSS) between 3 and 5 to include patients with overall neurological disability from mild to moderate.\n* Presence of one or more of the following cognitive disorders (reported by the patient and subsequently confirmed through the Oxford Cognitive Screen-OCS):\n* Memory disorders\n* Attention disorders\n* Executive function disorders\n* Availability of internet at the patient's home necessary for the tele-rehabilitation procedures.\n* Adequate visual and auditory abilities to use the rehabilitation device.\n\nExclusion Criteria:\n\n* Presence of other neurological conditions;\n* Psychiatric disorders in medical history;\n* Alcohol and\u002For drug abuse;\n* Presence of uncorrected severe visual deficits.","ALL","18 Years","65 Years",{"count":67,"type":68},60,"ESTIMATED","INTERVENTIONAL",[71],"NA","Non-Inferiority Study, Post-Market Clinical Investigation with a Device, Single-Blind Randomized Controlled Trial in a Cohort of Patients Diagnosed with Multiple Sclerosis (MS).\n\nThe aim of the study is to assess whether a computer-based cognitive treatment delivered via telerehabilitation produces effects from T0 to T1 that are not inferior to those of an in-person treatment on sustained attention in a cohort of patients with MS.\n\nThe secondary objective is to evaluate the effects of telerehabilitation compared to the same treatment delivered in person on attentional shifting, memory, executive functions, and daily functioning (including cognitive fatigue, quality of life, and mood) in patients with MS.",[9,74,75,76],"Multiple Sclerosis","Cognitive Disorders","Neurorehabilitation",[78,79,80],"telerehabilitation","multiple sclerosis","cognitive disorders","2025-04-30",{"date":83,"type":84},"2025-05-09","ACTUAL",{"date":86,"type":84},"2023-02-08",{"date":88,"type":68},"2025-09-30",{"name":5,"class":6},1]