[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639885":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":10,"responsibleParty":29,"collaborators":10,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":10,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":39,"maxAge":40,"enrollmentInfo":41,"targetDuration":44,"studyType":45,"phases":10,"briefSummary":46,"conditions":47,"keywords":10,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":10},{"fullName":5,"class":6},"Ningbo No.2 Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sports Injury Cohort",null,"Participants with knee-related sports injuries as the main clinical condition. This cohort will be observed for injury characteristics, treatment patterns, tissue repair, functional recovery, and subsequent degenerative changes during follow-up.",[13],"Other: Routine Clinical Care",{"label":15,"type":10,"description":16,"interventionNames":17},"Degenerative Knee Disease Cohort","Participants with degenerative knee conditions, including knee osteoarthritis or related degenerative disorders, as the main clinical condition. This cohort will be observed for degeneration severity, symptom burden, imaging progression, body composition, gait changes, and clinical outcomes during follow-up.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Routine Clinical Care","Participants will receive routine clinical care as determined by their treating physicians according to usual clinical practice. The study will not assign any treatment, randomization, or experimental intervention.",[15,9],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Yi Yuan, MD","CONTACT","+86 18858234093","yct1124@alumni.sjtu.edu.cn",{"type":30,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100639885","cohort-of-lower-extremity-sports-injuries-and-degenerationyongjiang-cohort-100639885",false,"NCT07592871","Cohort of Lower-Extremity Sports Injuries and Degeneration(Yongjiang Cohort)","Bidirectional Cohort of Lower-Extremity Sports Injuries and Degeneration (Yongjiang Cohort)","Inclusion Criteria:\n\n* Patients who plan to receive relevant clinical evaluation or treatment at Ningbo No. 2 Hospital and are able to complete baseline assessment.\n* Patients with a clinical diagnosis of knee-related injury or degenerative knee disease.\n* Patients who are willing to provide informed consent and participate in follow-up.\n\nExclusion Criteria:\n\n* Patients who are unable to complete the core baseline assessments or have substantial missing key clinical information.\n* Patients with severe comorbid conditions or cognitive impairment that may affect assessment of the main outcomes or prevent participation in follow-up.\n* Patients who are considered by the investigator to be unsuitable for inclusion in this cohort.","ALL","18 Years","90 Years",{"count":42,"type":43},500,"ESTIMATED","2 Years","OBSERVATIONAL","This is an observational cohort study conducted at Ningbo No. 2 Hospital. The study will include patients with knee-related sports injuries or degenerative knee conditions who receive routine clinical care. The purpose is to build a standardized real-world clinical cohort and evaluate knee injury, degeneration, recovery, and long-term outcomes.\n\nAfter informed consent, participants will undergo baseline data collection, including medical history, laboratory tests, questionnaires, X-ray and MRI imaging, and functional assessments. Patients younger than 50 years will mainly be assessed for sports injury and functional recovery, while patients aged 50 years or older will receive additional sarcopenia-related assessments such as grip strength, DXA testing, and gait evaluation.\n\nNo experimental treatment, randomization, or intervention will be assigned. Participants will be followed at about 6, 12, and 24 months after treatment or surgery to assess knee function, imaging changes, reinjury, reoperation, pain, quality of life, falls, and functional decline. The study plans to enroll about 500 participants.",[48],"Osteoarthritis (OA) of the Knee","NOT_YET_RECRUITING","2026-05-19",{"date":52,"type":53},"2026-05-22","ACTUAL",{"date":55,"type":43},"2026-06-01",{"date":57,"type":43},"2028-05-31",{"name":5,"class":6}]