[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599264":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":53,"collaborators":11,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":11,"enrollmentInfo":64,"targetDuration":11,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":75,"overallStatus":80,"whyStopped":11,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Ulcerative Colitis Group","ACTIVE_COMPARATOR",null,[13,14],"Other: Blood sample","Procedure: biopsy",{"label":16,"type":17,"description":11,"interventionNames":18},"Non-Ulcerative Colitis with Polyps Group","PLACEBO_COMPARATOR",[13,14],[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"Blood sample","3 blood samples",[16,9],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"PROCEDURE","biopsy","3 pairs of biopsy realised during the coloscopy",[16,9],[30],{"name":31,"affiliation":5,"role":32},"Pauline RIVIERE, MD","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":11,"email":37},"CONTACT","+335 57 65 64 39","pauline.riviere@chu-bordeaux.fr",[39],{"facility":40,"status":11,"city":41,"state":11,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"CHU de Bordeaux","Pessac","33604","France","FR",{"type":46,"coordinates":47},"Point",[48,49],-0.6324,44.80565,{"lat":49,"lon":48},[52],{"name":31,"role":35,"phone":36,"phoneExt":11,"email":37},{"type":54,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100599264","cohort-of-patients-with-ulcerative-colitis-or-polyps-followed-in-chu-de-bordeaux-associated-with-a-biocollection---colibri-100599264",false,"NCT07082231","Cohort of Patients With Ulcerative Colitis or Polyps Followed in CHU de Bordeaux Associated With a Biocollection - COLIBRI","COLIBRI","* Inclusion criteria:\n\n  * General Inclusion Criteria:\n\n    * Patients covered by a social security system.\n    * French-speaking patients.\n    * Patients aged ≥18 years.\n    * Patients who have provided free, informed, and written consent (no later than the inclusion day and before any research-related examination).\n  * Specific Inclusion Criteria for the UC Group:\n\n    * Patients diagnosed with ulcerative colitis (UC) according to the European Crohn's and Colitis Organisation (ECCO) guidelines.\n    * Patients undergoing lower gastrointestinal endoscopy or rectocolic surgery.\n  * Non-UC Patients with Polyps Group:\n\n    * Patients undergoing colonoscopy with resection of hyperplastic polyps in the rectum, sessile serrated lesions, or adenomas \\>2 cm.\n* Exclusion criteria:\n\n  * Patients with perianal, ileal lesions, or endoscopic features of colonic lesions suggestive of Crohn's disease.\n  * Pregnant or breastfeeding women.\n  * Patients under legal protection or unable to provide informed consent.\n  * Patients deprived of liberty by judicial or administrative decision, hospitalized without consent, or admitted to a healthcare or social institution for reasons unrelated to the study.","ALL","18 Years",{"count":65,"type":66},200,"ESTIMATED","INTERVENTIONAL",[69],"NA","Ulcerative colitis (UC) is a chronic disease characterized by acute episodes of bloody diarrhea with varying degrees of severity. The most feared event, acute severe UC, can lead to life-threatening and systemic complications. Little is known about the determinants of severity in UC. The investigators hypothesize that distinct severity phenotypes of UC arise from intricated host-microbiota mechanisms influencing repair mechanisms. Our first and main objective is to study the natural history of UC during a one-year time period in a cohort of patients.",[72,73,74],"Ulcerative Colitis","Inflammatory Bowel Disease (IBD)","Acute Severe Ulcerative Colitis",[76,77,78,79],"Acute severe ulcerative colitis","Ulcerative colitis","Inflammatory bowel disease","Biobank","NOT_YET_RECRUITING","2025-07-21",{"date":83,"type":84},"2025-07-24","ACTUAL",{"date":86,"type":66},"2025-09",{"date":88,"type":66},"2027-09",{"name":5,"class":6},1]