[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634767":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":56,"collaborators":58,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":84,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Westat","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pilot",null,"Activities: 1 enrollment survey, 1 post-donation survey, 3 monthly surveys, 4 feedback surveys (1-2 questions each) 3, 6mL WB collections, and acute illness surveys, if needed.",[13],"Procedure: Plasmapheresis Procedure",{"label":15,"type":10,"description":16,"interventionNames":17},"Main","Activities: 1 enrollment survey, 1 post-donation survey, up to 22 monthly surveys, up to 14, 6mL WB collections 2 annual surveys, and acute illness surveys, if needed.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","Plasmapheresis Procedure","Both pilot and main cohort will undergo plasmapheresis (plasma donation) as part of their initial visit for the study. Some participants will donate plasma throughout the duration of either cohort (3 months in pilot or up to 2 years in the main study.",[15,9],[25],{"name":26,"affiliation":5,"role":27},"Sarah Ball, PhD","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Holly Sawyer","CONTACT","706-825-7703","hollysawyer@westat.com",{"name":35,"role":31,"phone":10,"phoneExt":10,"email":36},"Kathy Chapman","kathychapman@westat.com",[38],{"facility":39,"status":10,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"ADMA Biocenters","Dallas","Georgia","30157","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-84.84077,33.92371,{"lat":49,"lon":48},[52],{"name":53,"role":31,"phone":54,"phoneExt":10,"email":55},"Marida Bivens, MBA","678-388-3309","mbivens@admabio.com",{"type":57,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[59],{"name":60,"class":61},"Plasma Protein Therapeutics Association","UNKNOWN","100634767","cohort-of-repeat-donor-experiences-core-study-100634767",false,"NCT07543965","Cohort of Repeat Donor Experiences (CORE) Study","Associations Between Frequent Plasmapheresis, Biomarkers, and Health Outcomes: A 2-Year National Prospective Cohort Study","CORE","Inclusion Criteria:\n\n* Aged 18-74;\n* Meet health and medical history requirements for being a plasma donor per eCFR::21 CFR 630.10 Subpart B -- General donor eligibility requirements;\n* Willing to provide phone number and mailing address; has access to internet-enabled smartphone device;\n* Plans to remain within local area during study duration; has not donated whole blood within past 12 months;\n* Does not have permanent deferral;\n* Has not donated plasma more than once at a non-participating plasma center;\n* Another member of their household is not enrolled.","ALL","18 Years","74 Years",{"count":74,"type":75},2090,"ESTIMATED","OBSERVATIONAL","The Plasma Protein Therapeutics Association (PPTA) sponsors the Cohort of Repeat Donor Experiences (CORE) Study. This is a prospective, observational cohort study that will follow Source Plasma donors for up to 2 years during the main study (anticipated to begin in summer 2026) and up to 3 months during the pilot launching in mid-March 2026. This study aims to confirm a lack of negative health effects Source Plasma donors may experience as a result of frequent plasmapheresis. The study will use data obtained through self-report surveys for the duration of the study along with periodic whole blood sample collections to test for CRP, ferritin, and IgG.",[79],"Health Effects (Ferritin Levels, CRP Levels, iGg Levels, Self-reported Health)",[81,82,83],"plasma","plasma-derived therapies","pharma","NOT_YET_RECRUITING","2026-04-14",{"date":87,"type":88},"2026-04-22","ACTUAL",{"date":90,"type":75},"2026-04-06",{"date":92,"type":75},"2029-04-30",{"name":5,"class":6},1]