[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628696":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":14,"collaborators":7,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":7,"eligibilityCriteria":22,"healthyVolunteers":23,"sex":24,"minAge":7,"maxAge":7,"enrollmentInfo":25,"targetDuration":7,"studyType":28,"phases":7,"briefSummary":29,"conditions":30,"keywords":7,"overallStatus":33,"whyStopped":7,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":7},{"fullName":5,"class":6},"The Second Affiliated Hospital of Chongqing Medical University","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Li ShiYing Deputy Chief Physician of the Department of Infectious Disease, Ph.D","CONTACT","0086+18623322462","302946@hospital.cqmu.edu.cn",{"type":15,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100628696","cohort-study-of-chronic-liver-disease-complicated-by-sepsis-100628696",false,"NCT07465003","Cohort Study of Chronic Liver Disease Complicated by Sepsis","Use of Antimicrobial Drugs in Severe Infections and Epidemiological Study of Populations With Severe Infections","Inclusion Criteria:\n\n* Clinically or pathologically diagnosed with cirrhosis;\n* meets the Sepsis-3 diagnostic criteria.\n\nExclusion Criteria:\n\n* Combined organ transplantation, active malignant tumors;\n* Pregnant or breastfeeding women;\n* Long-term use of immunosuppressants (non-steroidal);\n* Death or voluntary discharge within 24 hours of admission;\n* Incomplete data.",true,"ALL",{"count":26,"type":27},1600,"ESTIMATED","OBSERVATIONAL","Study population: Patients with liver cirrhosis complicated by sepsis Observation indicators: Fluid resuscitation strategy, early dynamic indicators such as MAP Observation endpoint: 28-day all-cause mortality Study design: Retrospective cohort study",[31,32],"Cirrhosis","Sepsis","NOT_YET_RECRUITING","2026-03-09",{"date":36,"type":37},"2026-03-11","ACTUAL",{"date":39,"type":27},"2026-02-25",{"date":41,"type":27},"2028-06-01",{"name":5,"class":6}]