[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606150":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":21,"locations":10,"responsibleParty":27,"collaborators":31,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":39,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":51,"studyType":52,"phases":10,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":10},{"fullName":5,"class":6},"China Academy of Chinese Medical Sciences","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Honghua Xiaoyao tablets",null,"The intervention for this cohort includes treatment with Honghua Xiaoyao Tablets.",[13],"Drug: Honghua Xiaoyao tablets",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DRUG","The non-exposed group (patients who did not receive Honghua Xiaoyao Tablets or other targeted drug treatments) only received routine clinical observation, and no drug intervention was applied after obtaining informed consent. If patients need to withdraw from the study due to their condition during the study period, on the premise that the patients have given full informed consent, doctors shall recommend other treatment regimens in accordance with clinical standards (when necessary, first-line drugs such as selective serotonin reuptake inhibitors (SSRIs) may be selected for intervention).",[9],[20],"serotonin reuptake inhibitors (SSRIs)",[22],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Lianxin Wang, Doctor of Medicine","CONTACT","86-13521781839","wlxing2022@163.com",{"type":28,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Lianxin Wang","Principal Investigator",[32,35],{"name":33,"class":34},"Chaoyangmen Community Health Service Center of Dongcheng District in Beijing","UNKNOWN",{"name":36,"class":34},"Hepingli Community Health Service Center,Dongcheng District,Beijing","100606150","cohort-study-of-honghua-xiaoyao-tablets-in-the-treatment-of-premenstrual-syndrome-based-on-target-trial-emulation-framework-100606150",false,"NCT07171814","Cohort Study of Honghua Xiaoyao Tablets in the Treatment of Premenstrual Syndrome Based on Target Trial Emulation Framework","Cohort Study of Honghua Xiaoyao Tablet in the Treatment of Premenstrual Syndrome Based on Target Trial Emulation Framework","TTE","Inclusion Criteria:\n\n1. Age:18-40 years old (both ends included);\n2. According to the 8th edition of \"Obstetrics and Gynecology\" (2014), patients diagnosed with premenstrual syndrome;\n3. In accordance with the TCM syndrome differentiation standard of liver depression and qi stagnation.\n\nExclusion Criteria:\n\n1. those who were allergic to the ingredients and excipients of Honghua Xiaoyao tablet (exposure group);\n2. In the non-exposed group, those receiving or planning to receive other targeted medications for PMS, such as serotonin reuptake inhibitors (SSRIs), hormones, etc.;\n3. irregular menstrual cycle (menstrual cycle not within 28±7 days);\n4. serious diseases of cardiovascular, cerebrovascular, hematopoietic system, liver and kidney, and malignant tumors;\n5. pregnant or lactating women, or those who plan to become pregnant within 6 months;\n6. patients with mental illness and alcohol or drug dependence; Patients with other complicated lesions were not eligible for this study.","FEMALE","18 Years","40 Years",{"count":49,"type":50},266,"ESTIMATED","4 Months","OBSERVATIONAL","To evaluate the efficacy and safety of Honghua Xiaoyao tablets in the treatment of premenstrual syndrome, and the results were further analyzed and evaluated by target trial simulation (TTE) framework.",[55],"Premenstrual Syndrome",[57,58,59],"Honghua Xiaoyao tablet","Target trial emulation","The real world","NOT_YET_RECRUITING","2025-09-06",{"date":63,"type":64},"2025-09-15","ACTUAL",{"date":66,"type":50},"2025-09-30",{"date":68,"type":50},"2027-09-30",{"name":29,"class":6}]