[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590698":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":83,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Azienda USL Modena","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cold snare polypectomy group","ACTIVE_COMPARATOR","For CSP, a 10 mm cold snare will be used (cold snare, Boston Scientific Corporation®, Marlborough, Massachusetts and cold snare, Meditalia S.A.S.®, Palermo, Italy); for CFP, a dedicated forceps will be used (Leviathan® cold forceps, 10 mm opening; Meditalia S.A.S., Palermo, Italy)",[13],"Device: Sampling from the resection margins",{"label":15,"type":16,"description":17,"interventionNames":18},"Cold forceps polypectomy group","EXPERIMENTAL","For CFP, Leviathan® will be used (Meditalia S.A.S., Palermo, Italy). The opening jaw reaches a 10 mm diameter, and the central section of each jaw has an enlarged diameter up to 3.6 mm compared to the oval axis, enhancing its capacity",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Sampling from the resection margins","After polypectomy, the base will be irrigated and assessed by the endoscopist, who may also use virtual or vital chromoendoscopy, if needed.\n\nAny residual adenomatous tissue will be removed using the same technique. To confirm the completeness of each polypectomy, two biopsies will be taken from the resection margins for polyps ≤ 5 mm, and three biopsies for polyps 6-9 mm, using standard biopsy forces.",[15,9],null,[27],{"name":28,"affiliation":29,"role":30},"Mauro Manno","AUSL Modena","PRINCIPAL_INVESTIGATOR",[32],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Noemi Gualandi","CONTACT","+39 059659500","gualandinoemi@gmail.com",[38],{"facility":29,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Carpi","Modena","41012","Italy","IT",{"type":45,"coordinates":46},"Point",[47,48],10.8777,44.78237,{"lat":48,"lon":47},[51],{"name":52,"role":34,"phone":53,"phoneExt":25,"email":54},"Mauro Manno, Principal investigator","+39 059659250","m.manno@ausl.mo.it",{"type":30,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Dr. Mauro Manno","Gastroenterology and Endoscopy Unit director","100590698","cold-snare-versus-cold-forceps-polypectomy-for-small-lesions-100590698",false,"NCT06970808","Cold Snare Versus Cold Forceps Polypectomy for Small Lesions","Cold SNAre Versus Cold forcePS Polypectomy for Small Colorectal Lesions (Cold-SNAPS): a Multicenter Randomized Trial","Cold-SNAPS","Inclusion Criteria:\n\n* Patients aged ≥ 18 years;\n* Ability to provide informed consent;\n* Presence of at least one colorectal polypoid\u002Fnon-polypoid lesion \\\u003C 10 mm\n\nExclusion Criteria:\n\n* Primary or secondary coagulopathy;\n* Improper interruption of dual antiplatelet therapy and\u002For antiplatelet therapy with P2Y12 receptor antagonists (clopidogrel, prasugrel, ticagrelor) and\u002For anticoagulant therapy;\n* Chronic inflammatory bowel diseases;\n* Inpatients undergoing colonoscopy;\n* Colonoscopy as part of regional colorectal cancer screening;\n* Pregnancy or breastfeeding",true,"ALL","18 Years",{"count":70,"type":71},312,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding peri- or post-procedural risks to the patient.\n\nThe main questions it aims to answer are:\n\n* Does the cold forceps guarantee a complete endoscopic resection rate?\n* How many adverse events could the jumbo forceps reduce in comparison to CSP?\n* Does the lesion retrieval rate increase?\n* Does the polypectomy duration decrease? Participants will be randomized to one or to the other group when a polypoid or non-polypoid lesion is identified. If multiple polyps are found in the same patient, they will be removed using the same polypectomy technique.\n\nIf polypectomy cannot be performed using the indicated technique, a crossover will be done according to the best practice of care principles.",[77,78],"Colorectal Adenoma","Colorectal Lesions",[80,81,82],"Cold forceps polypectomy","Colonoscopy","Cold snare polypectomy","NOT_YET_RECRUITING","2025-05-06",{"date":86,"type":87},"2025-05-14","ACTUAL",{"date":89,"type":71},"2025-12",{"date":91,"type":71},"2027-12",{"name":5,"class":6},1]