[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618335":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":63,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":26,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":84,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cold Water","EXPERIMENTAL","• Cold Water Irrigation of the Papilla: Participants randomized to the experimental arm will receive 250 mL of refrigerated water (target temperature 4-8 °C) in five 50 mL aliquots directed toward the papilla, with duodenal aspiration after each aliquot.",[13],"Procedure: Cold water",{"label":15,"type":16,"description":17,"interventionNames":18},"Warm water","PLACEBO_COMPARATOR","• Control Intervention: Participants randomized to the control group will receive 250 mL of room-temperature water in identical increments and delivery.",[19],"Procedure: Warm water",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Cold water","Rectal indomethacin plus cold water irrigation",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Rectal indomethacin plus room-temperature water irrigation",[15],[31],{"name":32,"affiliation":33,"role":34},"Reza Hejazi","University of Kansas","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","913-588-6019","rhejazi@kumc.edu",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Roham Salman Roghani","Salman Roghani","rsalmanroghani@kumc.edu",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"University of Kansas Cancer Center","RECRUITING","Kansas City","Kansas","66160","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-94.62746,39.11417,{"lat":57,"lon":56},[60,61,62],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},{"name":41,"role":37,"phone":38,"phoneExt":26,"email":43},{"name":32,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":34,"investigatorFullName":32,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Associate Professor","100618335","cold-water-irrigation-therapy-as-an-adjunct-to-indomethacin-for-post-endoscopic-retrograde-cholangiopancreatographyercp-pancreatitis-100618335",false,"NCT07330284","Cold Water Irrigation Therapy as an Adjunct to Indomethacin for Post-Endoscopic Retrograde Cholangiopancreatography(ERCP) Pancreatitis","Adjunctive Cold Water Irrigation Added to Rectal Indomethacin for Prevention of Post- Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis","Inclusion Criteria:\n\n* Native papilla present.\n* Undergoing ERCP for diagnostic or therapeutic indications.\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Post-operative reconstructed intestinal tract other than Billroth I reconstruction.\n* Acute pancreatitis at the time of ERCP.\n* Chronic pancreatitis.\n* Pancreatic head cancer with occlusion of the main pancreatic duct.\n* Existing pancreatic duct stent or need for prophylactic pancreatic duct stenting during the index ERCP.\n* Known contraindications or allergy to indomethacin or other NSAIDs.\n* Significant renal impairment (eGFR \\\u003C 30 mL\u002Fmin\u002F1.73m²).\n* Active peptic ulcer disease or history of NSAID-induced gastrointestinal bleeding.","ALL","20 Years",{"count":75,"type":76},950,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study is designed to learn whether rinsing the papilla with cold water at the end of an ERCP procedure, in addition to standard medicine, can help lower the chance of developing pancreatitis, which is the most common major complication after ERCP.",[82,83],"Pancreatitis","ERCP Surgery",[9,85,86,82],"Prevention","ERCP","2026-05-04",{"date":89,"type":90},"2026-05-07","ACTUAL",{"date":92,"type":90},"2025-12-05",{"date":94,"type":76},"2029-12",{"name":5,"class":6},1]